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tributyrin

Known as: Butanoic Acid, 1,2,3-Propanetriyl Ester, 1,2,3-Propanetriyl Butanoate, Butanoic Acid 1,2,3-Propanetriyl Ester 
A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone… 
National Institutes of Health

Related topics

Related topics

7 relations
Histone DeacetylaseHistone DeacetylationInhibition of Cell ProliferationNCIt Antineoplastic Agent Terminology

Broader (1)

Triglycerides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Aberystwyth University Isolation and characterization of novel lipases/esterases from a bovine rumen metagenome
Improving the health beneficial fatty acid content of meat and milk is a major challenge requiring an increased understanding of… 
1994
1994
Purification and characterization of a thermostable carboxylesterase from the thermoacidophilic eubacterium Bacillus acidocaldarius.
A thermostable carboxylesterase from the thermoacidophilic eubacterium Bacillus acidocaldarius was isolated, purified 1800-fold… 
Highly Cited
1983
Highly Cited
1983
Low-melting phenytoin prodrugs as alternative oral delivery modes for phenytoin: a model for other high-melting sparingly water-soluble drugs.
Phenytoin is a high-melting, weakly acidic, and sparingly water-soluble drug. Because of these physicochemical properties… 
1976
1976
Esterolytic activities of rat intestinal mucosa. 2. Purification and properties of a glycerol-ester hydrolase.
A glycerol-ester hydrolase from rat intestinal cells has been purified using chromatography on carboxyhexanoyl-Sepharose… 
1973
1973
The influence of chemical modification on the hydrolysis of fats by pancreatic lipase and pregastric esterase with reference to fat digestion in the pre-ruminant calf.
The hydrolysis of various dietary fats and pure triglycerides by pregastric esterase and pancreatic lipase was studied in vitro… 
Highly Cited
1967
Highly Cited
1967
Purification and characterization of the lipase of Pseudomonas fragi.
SUMMARY The lipase of Pseudomonas fragi (NRRL B-25) was purified 75- to Ioo-fold with an overall recovery of ca. 20 %. The enzyme… 
Highly Cited
1965
Highly Cited
1965
GEL FILTRATION APPLIED TO THE STUDY OF LIPASES AND OTHER ESTERASES.
1. Sephadex G-100 and G-200 gel-filtration columns were calibrated for molecular-weight estimation with proteins of known… 
1957
1957
Effect of tributyrin on circulation and respiration.
Summary. The effects of tributyrin on circulation and respiration have been studied by injection of a tributyrin emulsion… 
1956
1956
Serum lipase determination; four-hour technic with olive oil substrate.
A method for determining serum lipase activity requiring only 4 hours incubation at 37° is given. Olive oil in a phosphate buffer… 
Highly Cited
1949
Highly Cited
1949
The measurement of the cytochrome oxidase activity of enzyme preparations.
containing 1 ml. 15 % glycerol solution, 1-0 ml. 0-1 M-sodium acetate, 0-5 ml. 0-3 M-bicarbonate solution and 0 5 ml. of the… 
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