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triazinate

Known as: Benzenesulfonyl fluoride, 3-chloro-4-[4-[2-chloro-4-(4, 6-diamino-2,2-dimethyl-1,3,5-triazin-1(2H)-yl)phenyl]butyl]-, monoethanesulfonate (9CI), ethanesulfonic acid, compd.with 3-((2-chloro-4-(4,6-diamino-2,2-dimethyl-1,3,5-triazin-1(2H)-yl)phenoxy)methyl)-N,N-dimethylben zamide (1:1), ethanesulfonic acid, compd. with 3-chloro-4-[4-[2-chloro-4-(4, 6-diamino-2, 2-dimethyl-s-triazin-1(2H)-yl)phenyl]butyl]benzenesulfonyl fluoride (1:1)(8CI) 
A synthetic dihydrotriazine derivative with antineoplastic properties. As an antifolate agent related to methotrexate (MTX), triazinate inhibits the… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (3)

Antineoplastic AgentsFolic Acid AntagonistsTriazines

Narrower (3)

Baker's AntifolNSC 127755NSC 139105
carmustine/triazinatedoxorubicin/fluorouracil/mitomycin/triazinateisplatin/cyclophosphamide/doxorubicin/triazinate

Papers overview

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2006
2006
Solvent dependent conformational relaxation of cis-1,3,5-hexatriene.
Ultrafast transient absorption spectroscopy was used to study the conformational relaxation dynamics of 1,3,5-cis-hexatriene (Z… 
2005
2005
GrefÄ\verÄnderungen bei Meningitis und ihre Bedeutung für die Pathogenese frühkindlicher HirnschÄden
Einleitung. Bei ei~rigen und ]ymphocyt~ren Meningi~iden versehiedenster ~tiologie, wie sie ein grSl~eres Kriegsund… 
2003
2003
BM-573, a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, Prevents Pig Myocardial Infarction Induced by Coronary Thrombosis
The aim of this study was to characterize the effects of BM-573 [N-terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl… 
1989
1989
Results of combination chemotherapy and thoracic radiation therapy for unresectable non-small cell carcinoma of the lung.
1982
1982
Specificity and reactivity of human leukocyte elastase, porcine pancreatic elastase, human granulocyte cathepsin G, and bovine pancreatic chymotrypsin with arylsulfonyl fluorides. Discovery of a new…
1982
1982
Agricultural droughts and crop production in the Indian arid zone
SummaryBased on a rational approach, agricultural droughts were studied for the period 1901–75 for 5 selected regions in the… 
1977
1977
A phase II study of triazinate (NSC 139105) in advanced colorectal carcinoma
Triazinate (Baker's Antifol, NSC 139105) was given to 28 patients as a single agent in the chemotherapy of advanced colerectal… 
1976
1976
Clinical and pharmacological evaluation of triazinate in humans.
Twenty-four patients with advanced solid tumors and seven with acute leukemia were treated with a triazine folate antagonist… 
1974
1974
Kinetics of inactivation of alpha-chymotrypsin with substituted benzenesulfonyl fluorides.
1958
1958
Zur Mechanik der mehrschichtigen Spanplatte
  • R. Keylwerth
  • Holz als Roh- und Werkstoff
  • 1958
  • Corpus ID: 24560929
SummaryWith a view to the economic importance of multi-layer sandwich boards and plastic layer boards from wood base materials… 
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