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transcription factor TFIIH

Known as: Transcription Factor BTF2, Basic Transcription Factor 2, Transcription Factor IIH 
TFIIH is a multisubunit factor consisting of at least 5 polypeptides of 92, 62, 43, 40, and 35 kD. The nonphosphorylated form of RNA polymerase II is… 
National Institutes of Health

Related topics

Related topics

30 relations
Basal transcription factor genesCDK-Activating Kinase Assembly Factor MAT1CDK7 protein, humanDNA Excision Repair Protein ERCC-2

Narrower (1)

DMP52 protein, Drosophila

Broader (1)

GTF2H4 gene

Papers overview

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2007
2007
Spliced Leader RNA Gene Transcription in Trypanosoma brucei Requires Transcription Factor TFIIH
ABSTRACT Trypanosomatid parasites share a gene expression mode which differs greatly from that of their human and insect hosts… 
Highly Cited
2005
Highly Cited
2005
TFIIH Operates through an Expanded Proximal Promoter To Fine-Tune c-myc Expression
ABSTRACT A continuous stream of activating and repressing signals is processed by the transcription complex paused at the… 
Highly Cited
2003
Highly Cited
2003
Tumor suppressor p53 dependent recruitment of nucleotide excision repair factors XPC and TFIIH to DNA damage.
2003
2003
Revised Subunit Structure of Yeast Transcription Factor IIH (TFIIH) and Reconciliation with Human TFIIH*
Tfb4 is identified as a subunit of the core complex of yeast RNA polymerase II general transcription factor IIH (TFIIH) by… 
Highly Cited
2001
Highly Cited
2001
A temperature-sensitive disorder in basal transcription and DNA repair in humans
The xeroderma pigmentosum group D (XPD) helicase subunit of TFIIH functions in DNA repair and transcription initiation. Different… 
Highly Cited
1999
Highly Cited
1999
RNA synthesis block by 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells
Most modern chemo- and radiotherapy treatments of human cancers use the DNA damage pathway, which induces a p53 response leading… 
1996
1996
Subunits of Yeast RNA Polymerase II Transcription Factor TFIIH Encoded by the CCL1 Gene (*)
Both 45- and 47-kDa subunits of TFIIK, a subcomplex of RNA polymerase II general transcription factor TFIIH, are encoded by the… 
Highly Cited
1995
Highly Cited
1995
The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.
EBNA 2 (Epstein-Barr virus nuclear antigen 2) is an acidic transactivator essential for EBV transformation of B lymphocytes. We… 
Highly Cited
1994
Highly Cited
1994
RNA polymerase transcription factor IIH holoenzyme from yeast.
Highly Cited
1994
Highly Cited
1994
Multiple sets of basal factors initiate transcription by RNA polymerase II.
The minimal requirements for transcription initiation from supercoiled templates were determined for the two major forms of TATA… 
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