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transcription factor TFIIH

Known as: Transcription Factor BTF2, Basic Transcription Factor 2, Transcription Factor IIH 
TFIIH is a multisubunit factor consisting of at least 5 polypeptides of 92, 62, 43, 40, and 35 kD. The nonphosphorylated form of RNA polymerase II is… Expand
National Institutes of Health

Related topics

Related topics

30 relations
Basal transcription factor genesCDK-Activating Kinase Assembly Factor MAT1CDK7 protein, humanDNA Excision Repair Protein ERCC-2
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Narrower (1)

DMP52 protein, Drosophila

Broader (1)

GTF2H4 gene

Papers overview

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Review
2018
Review
2018
The essential and multifunctional TFIIH complex
TFIIH is a 10‐subunit complex that regulates RNA polymerase II (pol II) transcription but also serves other important biological… Expand
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Highly Cited
2004
Highly Cited
2004
TFIIH Transcription Factor, a Target for the Rift Valley Hemorrhagic Fever Virus
The Rift Valley fever virus (RVFV) is the causative agent of fatal hemorrhagic fever in humans and acute hepatitis in ruminants… Expand
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Highly Cited
2003
Highly Cited
2003
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity.
Set1, the yeast histone H3-lysine 4 (H3-K4) methylase, is recruited by the Pol II elongation machinery to a highly localized… Expand
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Highly Cited
2000
Highly Cited
2000
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription.
The activities of several mRNA processing factors are coupled to transcription through binding to RNA polymerase II (Pol II). The… Expand
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Highly Cited
1999
Highly Cited
1999
Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.
To understand the initiation of the transcription of protein-coding genes, we have dissected the role of the basal transcription… Expand
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Highly Cited
1997
Highly Cited
1997
Stimulation of RARα Activation Function AF-1 through Binding to the General Transcription Factor TFIIH and Phosphorylation by CDK7
The activity of the N-terminal activation function AF-1 of RAR alpha1 is abrogated upon mutation of a phosphorylatable serine… Expand
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Highly Cited
1995
Highly Cited
1995
Cdk-activating kinase complex is a component of human transcription factor TFIIH
TRANSCRIPTION factor IIH (TFIIH) contains a kinase capable of phosphorylating the carboxy-terminal domain (CTD) of the largest… Expand
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Highly Cited
1995
Highly Cited
1995
Association of Cdk-activating kinase subunits with transcription factor TFIIH
THE RNA polymerase II large subunit contains an essential carboxy-terminal domain (CTD) believed to be involved in the response… Expand
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Highly Cited
1994
Highly Cited
1994
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
A mediator was isolated from yeast that enabled a response to the activator proteins GAL4-VP16 and GCN4 in a transcription system… Expand
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Highly Cited
1994
Highly Cited
1994
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
KIN28, a member of the p34cdc2/CDC28 family of protein kinases, is identified as a subunit of yeast RNA polymerase transcription… Expand
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