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CDK7 protein, human

Known as: CDK-Activating Kinase 1, CDKN7 protein, human, Cyclin-Dependent Kinase 7 
Cyclin-dependent kinase 7 (346 aa, ~39 kDa) is encoded by the human CDK7 gene. This protein is involved in the mediation of protein phosphorylation… 
National Institutes of Health

Related topics

Related topics

24 relations
Basal transcription factor genesCDK7 geneCDK7 wt AlleleCell Cycle Control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Cyclin H binding to the RARalpha activation function (AF)-2 domain directs phosphorylation of the AF-1 domain by cyclin-dependent kinase 7.
The transcriptional activity of nuclear retinoic acid receptors (RARs), which act as RAR/retinoid X receptor (RXR) heterodimers… 
2005
2005
An Alliance between Ras GTPase-activating Protein, Filamin C, and Ras GTPase-activating Protein SH3 Domain-binding Protein Regulates Myocyte Growth*
We have previously reported that Ras GTPase-activating protein (RasGAP) is involved in a pathway that regulates total cellular… 
Highly Cited
2002
Highly Cited
2002
Adenosine Monophosphoramidase Activity of Hint and Hnt1 Supports Function of Kin28, Ccl1, and Tfb3* 210
The histidine triad superfamily of nucleotide hydrolases and nucleotide transferases consists of a branch of proteins related to… 
Highly Cited
2000
Highly Cited
2000
Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa.
Cyclin-dependent kinases (CDKs) function as central regulators of both the cell cycle and transcription. CDK activation depends… 
Highly Cited
1999
Highly Cited
1999
Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.
Activating phosphorylation of cyclin-dependent protein kinases (CDKs) is necessary for their kinase activity and cell cycle… 
Highly Cited
1998
Highly Cited
1998
Cak1 Is Required for Kin28 Phosphorylation and Activation In Vivo
ABSTRACT Complete activation of most cyclin-dependent protein kinases (CDKs) requires phosphorylation by the CDK-activating… 
Highly Cited
1997
Highly Cited
1997
The CDK‐activating kinase CAK1 can dosage suppress sporulation defects of smk1 MAP kinase mutants and is required for spore wall morphogenesis in Saccharomyces cerevisiae
Mitogen‐activated protein (MAP) kinase pathways are evolutionarily conserved kinase cascades that are required for the response… 
Highly Cited
1996
Highly Cited
1996
The Cdk-Activating Kinase (CAK) from Budding Yeast
Highly Cited
1994
Highly Cited
1994
Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.
Using polymerase chain reaction (PCR)-based methods, we have isolated cDNA clones of two new members of serine/threonine kinases… 
Highly Cited
1992
Highly Cited
1992
Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium.
K1 is a monoclonal antibody that reacts with a cell surface antigen (CAK1) found in human mesothelia and nonmucinous ovarian… 
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