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CDK7 gene

Known as: CYCLIN-DEPENDENT KINASE 7, CAK1, SERINE/THREONINE PROTEIN KINASE 1 
This gene is involved in the regulation of the cell cycle and RNA polymerase II-mediated transcription.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The MYC oncoproteins are thought to stimulate tumor cell growth and proliferation through amplification of gene transcription, a… Expand
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Highly Cited
2014
Highly Cited
2014
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state… Expand
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Review
2005
Review
2005
In metazoans, cyclin-dependent kinase 7 (CDK7) has essential roles in both the cell-division cycle and transcription, as a CDK… Expand
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Review
2003
Review
2003
Xeroderma pigmentosum (XP), Cockayne syndrome (CS) and trichothiodystrophy (TTD) are genetic disorders with very different… Expand
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Highly Cited
1995
Highly Cited
1995
THE RNA polymerase II large subunit contains an essential carboxy-terminal domain (CTD) believed to be involved in the response… Expand
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Highly Cited
1995
Highly Cited
1995
A second protein-tyrosine kinase (PTK) of the focal adhesion kinase (FAK) subfamily, cell adhesion kinase β (CAKβ), was… Expand
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Highly Cited
1994
Highly Cited
1994
Phosphorylation by the CDK-activating kinase (CAK) is a required step in the activation of cyclin-dependent kinases. We have… Expand
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Highly Cited
1994
Highly Cited
1994
The vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cAMP-dependent- (cAK) and cGMP-dependent protein kinase… Expand
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Highly Cited
1994
Highly Cited
1994
KIN28, a member of the p34cdc2/CDC28 family of protein kinases, is identified as a subunit of yeast RNA polymerase transcription… Expand
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Highly Cited
1993
Highly Cited
1993
Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for… Expand
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