CDK7 gene

Known as: CYCLIN-DEPENDENT KINASE 7, CAK1, SERINE/THREONINE PROTEIN KINASE 1 
This gene is involved in the regulation of the cell cycle and RNA polymerase II-mediated transcription.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that exhibits extremely high levels of genetic… (More)
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Highly Cited
2014
Highly Cited
2014
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state… (More)
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Highly Cited
2014
Highly Cited
2014
The MYC oncoproteins are thought to stimulate tumor cell growth and proliferation through amplification of gene transcription, a… (More)
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Review
2010
Review
2010
Protein phosphorylation is a key regulatory mechanism for cell cycle control in eukaryotes. From yeast to humans, cell cycle… (More)
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Highly Cited
2007
Highly Cited
2007
Molecular mechanisms of cell-cycle arrest caused by gambogic acid (GA), a natural product isolated from the gamboge resin of… (More)
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Review
2005
Review
2005
In metazoans, cyclin-dependent kinase 7 (CDK7) has essential roles in both the cell-division cycle and transcription, as a CDK… (More)
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Highly Cited
1997
Highly Cited
1997
The activity of the N-terminal activation function AF-1 of RAR alpha1 is abrogated upon mutation of a phosphorylatable serine… (More)
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Highly Cited
1997
Highly Cited
1997
The cyclin-dependent kinase (CDK)-activating kinase CAK has been proposed to function in the control of cell cycle progression… (More)
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Highly Cited
1996
Highly Cited
1996
A series of 195 human gliomas were studied as to the status of their CDKN2A, CDK4 and RB1 genes. Among 120 glioblastomas, 40% had… (More)
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Highly Cited
1994
Highly Cited
1994
The vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cAMP-dependent- (cAK) and cGMP-dependent protein kinase… (More)
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