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tralokinumab

 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Background: IL‐13 has an important role in atopic dermatitis (AD) pathogenesis. Tralokinumab is a fully human mAb that potently… Expand
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2018
2018
BACKGROUND The role of interleukin 13 in airway inflammation and remodelling in asthma is unclear. Tralokinumab is a human… Expand
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Highly Cited
2018
Highly Cited
2018
BACKGROUND Tralokinumab is an anti-interleukin-13 human monoclonal antibody developed for the treatment of severe, uncontrolled… Expand
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2018
2018
Rationale: IL‐13 is a potential therapeutic target for idiopathic pulmonary fibrosis (IPF); preclinical data suggest a role in… Expand
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2017
2017
Interleukin (IL)-13 is a pleiotropic T helper type 2 cytokine frequently associated with asthma and atopic dermatitis. IL-13… Expand
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2017
2017
Abstract not available. Disclosures:  Study sponsored by LEO Pharma Copyright 2018 SKIN 
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Interleukin 13 is a central mediator of asthma. Tralokinumab is a human interleukin-13 neutralising monoclonal… Expand
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Highly Cited
2014
Highly Cited
2014
Objective Interleukin-13 (IL-13) has been implicated as a key driver of UC. This trial evaluates the efficacy and safety of… Expand
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Highly Cited
2014
Highly Cited
2014
The aberrant fibrotic and repair responses in the lung are major hallmarks of idiopathic pulmonary fibrosis (IPF). Numerous… Expand
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Highly Cited
2012
Highly Cited
2012
Pre-clinical data demonstrate a pivotal role for interleukin (IL)-13 in the development and maintenance of asthma. This study… Expand
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