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toxopyrimidine

Known as: 2-M-4-A-5-HMP, 4-A-2-MEP, 4-amino-2-methyl-5-hydroxymethylpyrimidine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Pyrimidines

Narrower (1)

toxopyrimidine monohydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Determination of the genetic, molecular, and biochemical basis of the Arabidopsis thaliana thiamin auxotroph th1.
Review
2006
Review
2006
Recent progress in understanding thiamin biosynthesis and its genetic regulation in Saccharomyces cerevisiae
  • K. Nosaka
  • Applied Microbiology and Biotechnology
  • 2006
  • Corpus ID: 904907
The yeast Saccharomyces cerevisiae is able to synthesize thiamin pyrophosphate (TPP) de novo, which involves the independent… 
Highly Cited
2006
Highly Cited
2006
Structure of the Thiazole Biosynthetic Enzyme THI1 from Arabidopsis thaliana*
Thiamin pyrophosphate is an essential coenzyme in all organisms that depend on fermentation, respiration or photosynthesis to… 
Highly Cited
2005
Highly Cited
2005
Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Bacillus subtilis gene products TenA and TenI have been implicated in regulating the production of extracellular proteases, but… 
Highly Cited
2004
Highly Cited
2004
A Genetic Screen for the Identification of Thiamin Metabolic Genes*
A genetic screen was developed for the identification of genes related to thiamin biosynthesis and degradation. Genes conferring… 
Highly Cited
2004
Highly Cited
2004
Biosynthesis of the thiamin pyrimidine: the reconstitution of a remarkable rearrangement reaction.
The conversion of 5-aminoimidazole ribonucleotide (AIR) into 4-amino-2-methyl-5-hydroxymethylpyrimidine (HMP) is a fascinating… 
1999
1999
Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution.
The crystal structure of Bacillus subtilis thiamin phosphate synthase complexed with the reaction products thiamin phosphate and… 
1992
1992
A positive regulatory gene, THI3, is required for thiamine metabolism in Saccharomyces cerevisiae
We have isolated a thiamine auxotrophic mutant carrying a recessive mutation which lacks the positive regulatory gene, THI3… 
Highly Cited
1991
Highly Cited
1991
Biosynthesis of the thiazole moiety of thiamin (vitamin B1) in higher plant chloroplasts.
The chloroplast stromal proteins from spinach condense the two heterocyclic moieties of vitamin B1--4-methyl-5-(beta-hydroxyethyl… 
1960
1960
The biosynthesis of thiamine. 1. Enzymatic formation of thiamine and phosphate esters of the pyrimidine moiety of thiamine.
The biosynthesis of thiamine appears to be accomplished with the initial formation of the pyrimidine and thiazole moieties by… 
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