tolmesoxide

Known as: 1,2-dimethoxy-4-methyl-5-(methylsulfinyl)benzene, 4,5-dimethoxy-o-tolyl methylsulfoxide

National Institutes of Health

Papers overview

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2004

SummaryA high pressure liquid chromatographic assay was developed for simultaneous measurement of the plasma levels of…

2004

SummaryThe pharmacokinetics, hypotensive effect and tolerability of a new vasodilator, tolmesoxide (T), have been studied in 6…

2004

SummaryThe haemodynamic response and pharmacokinetics of single dose oral tolmesoxide were studied at various dose levels in 4…

1995

The effects of age on the disposition and hemodynamic responses to the direct acting vasodilator tolmesoxide were examined in an…

1986

1 The haemodynamic, metabolic and regional blood flow effects of the vasodilator, tolmesoxide (1 mg kg−1 min−1 for 20 min by…

1981

1 The effect was studied of tolmesoxide (Rx71107), a tolmesoxide metabolite (Rx71112) and nifedipine on active tension in human…

1981

Tolmesoxide, a potent vasodilating compound, was infused intravenously (0.5 to 3.5 mg/kg b.w., rate of infusion: 2.5 to 10.0 mg…

1981

1. The excretion and metabolism of tolmesoxide ((4,5-dimethoxy-2-methylphenyl)-methylsulphoxide) has been studied in rat, dog and…

1980

Data, obtained by invasive hemodynamic monitoring, are now routinely available in our Intensive Care Unit, and are processed by…

1978

1 The blood pressure of conscious normotensive, deoxycorticosterone acetate (DOCA) hypertensive and 1 kidney Goldblatt…