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toll-like receptor 4

Known as: Toll-4 Receptor, Toll Like Receptor 4, TLR4 Receptor 
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE… 
National Institutes of Health

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Endotoxin HyporesponsivenessTLR4 protein, human
In BloodTLR2 protein, humanTLR4 geneagonists

Papers overview

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2015
2015
Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk
Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of… 
2012
2012
Ischemia and Reperfusion Liver Injury is Reduced in the Absence of Toll-like Receptor 4
Background/Aims: Toll-like receptor 4 (TLR4) is expressed on hepatic non-parenchymal cells and hepatocytes. Hepatic signaling… 
2012
2012
Effects of penehyclidine hydrochloride on pulmonary contusion from blunt chest trauma in rats.
2008
2008
Regulation of Hepatic Drug-Metabolizing Enzyme Genes by Toll-Like Receptor 4 Signaling Is Independent of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein
During inflammation, drug metabolism and clearance are altered due to suppression of hepatic drug-metabolizing enzyme (DME) genes… 
2008
2008
Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression
Objective Toll-like receptor 4 (TLR4) is the main receptor for Lipopolysaccharide (LPS). Two relatively common variants of the… 
Highly Cited
2007
Highly Cited
2007
Evidence for association between a Toll-like receptor 4 gene polymorphism and moderate/severe periodontitis in the Japanese population.
BACKGROUND AND OBJECTIVE Chronic periodontitis is an inflammatory disease caused by bacteria in subgingival pockets. Because Toll… 
2007
2007
The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.
BACKGROUND Recently, the common Asp299Gly polymorphism of the Toll-like receptor 4 (TLR-4) was found to be associated with a… 
Highly Cited
2005
Highly Cited
2005
Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis.
Highly Cited
2004
Highly Cited
2004
Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis
ABSTRACT Lipopolysaccharide (LPS) signaling is critical for the innate immune response to gram-negative bacteria. Here, evidence… 
2004
2004
Disruption of membrane cholesterol stimulates MyD88-dependent NF-kappaB activation in immature B cells.
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