TLR2 protein, human

Known as: TIL4, Toll-Like Receptor 2, TLR2 
Toll-like receptor 2 (784 aa, ~90 kDa) is encoded by the human TLR2 gene. This protein is involved in signal transduction that modulates innate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Microglia activated by extracellularly deposited amyloid β peptide (Aβ) act as a two-edged sword in Alzheimer's disease… (More)
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Highly Cited
2012
Highly Cited
2012
Specific intestinal microbiota has been shown to induce Foxp3(+) regulatory T cell development. However, it remains unclear how… (More)
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Highly Cited
2010
Highly Cited
2010
Obesity and its associated comorbidities, termed metabolic syndrome, are increasingly prevalent, and they pose a serious threat… (More)
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Highly Cited
2007
Highly Cited
2007
TLRs are an evolutionarily conserved family of cell membrane proteins believed to play a significant role in innate immunity and… (More)
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Highly Cited
2007
Highly Cited
2007
Dying cells stimulate inflammation, and this response is thought to contribute to the pathogenesis of many diseases. Very little… (More)
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Highly Cited
2006
Highly Cited
2006
Activation of innate immune cells by Trypanosoma cruzi-derived molecules such as GPI anchors and DNA induces proinflammatory… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The mechanism of stimulation of human gingival epithelial cells (HGEC) by Porphyromonas gingivalis (Pg) has not been… (More)
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Highly Cited
2001
Highly Cited
2001
Lipopolysaccharide (LPS) derived from the periodontal pathogen Porphyromonas gingivalis has been reported to differ structurally… (More)
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Highly Cited
2000
Highly Cited
2000
Toll-like receptor (TLR) 2 has recently been associated with cellular responses to numerous microbial products, including LPS and… (More)
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Highly Cited
1998
Highly Cited
1998
Bacterial lipopolysaccharide (LPS) induces activation of the transcription factor nuclear factor kappaB (NF-kappaB) in host cells… (More)
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