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Leucine-Rich Repeat

Known as: Right-Handed Beta-Alpha Superhelix, Leucine Rich Repeat, LRR 
A leucine-rich protein structural motif that forms an alpha/beta horseshoe tertiary structure. It is composed of repeating units of 20-30 amino acid… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Parkinson disease (PD) treatment options have conventionally focused on dopamine replacement and provision of symptomatic relief… Expand
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Review
2019
Review
2019
James Parkinson first described the motor symptoms of the disease that took his name over 200 years ago. While our knowledge of… Expand
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Review
2019
Review
2019
ABSTRACT Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating… Expand
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Review
2019
Review
2019
Parkinson's disease (PD) is a typical neurodegenerative disease and the pathological feature of which is the death of dopamine… Expand
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Review
2018
Review
2018
Inflammation is an important driver of atherosclerosis, the underlying pathology of cardiovascular diseases. Therefore… Expand
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Highly Cited
2005
Highly Cited
2005
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's disease (PD) with a clinical appearance… Expand
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Review
2003
Review
2003
Toll-like receptors (TLRs) are the major cell-surface initiators of inflammatory responses to pathogens. They bind a wide variety… Expand
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Highly Cited
2001
Highly Cited
2001
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand
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Review
2001
Review
2001
Leucine-rich repeats (LRRs) are 20-29-residue sequence motifs present in a number of proteins with diverse functions. The primary… Expand
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Highly Cited
1994
Highly Cited
1994
Plant disease resistance genes function is highly specific pathogen recognition pathways. PRS2 is a resistance gene of… Expand
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