Leucine-Rich Repeat

Known as: Right-Handed Beta-Alpha Superhelix, Leucine Rich Repeat, LRR 
A leucine-rich protein structural motif that forms an alpha/beta horseshoe tertiary structure. It is composed of repeating units of 20-30 amino acid… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Inflammation affects all stages of tumorigenesis. A key signaling pathway leading to acute and chronic inflammation is through… (More)
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Review
2017
Review
2017
Drug-induced acute liver failure carries a high morbidity and mortality rate. Acetaminophen overdose is the number one cause of… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's disease (PD) with a clinical appearance… (More)
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Highly Cited
2005
Highly Cited
2005
Parkinson's disease (PD) is a disorder of movement, cognition, and emotion, and it is characterized pathologically by neuronal… (More)
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Review
2003
Review
2003
Toll-like receptors (TLRs) are the major cell-surface initiators of inflammatory responses to pathogens. They bind a wide variety… (More)
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Highly Cited
2001
Highly Cited
2001
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… (More)
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Review
2001
Review
2001
Leucine-rich repeats (LRRs) are 20-29-residue sequence motifs present in a number of proteins with diverse functions. The primary… (More)
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Highly Cited
1998
Highly Cited
1998
The superfamily of leucine-rich repeat proteins can be subdivided into at least six subfamilies, characterised by different… (More)
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Highly Cited
1997
Highly Cited
1997
The first somatic single cells of carrot hypocotyl explants having the competence to form embryos in the presence of 2,4… (More)
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Highly Cited
1996
Highly Cited
1996
In plants, resistance to pathogens is frequently determined by dominant resistance genes, whose products are proposed to… (More)
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