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tisopurine

Known as: 4-mercaptopyrazolo(3,4-d)pyrimidine, thiopurinol 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AllopurinolGout Suppressants
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Reaction of nontoxic, potentially chemopreventive purinethiols with a direct-acting, electrophilic carcinogen, benzo[a]pyrene-7,8-diol 9,10-epoxide.
Several nontoxic purinethiols have been shown to block the ability of the carcinogen 7-r,8-t-dihydroxy-9-t,10-t-oxy-7,8,9,10… 
1991
1991
Inhibition by 2,6-dithiopurine and thiopurinol of binding of a benzo(a)pyrene diol epoxide to DNA in mouse epidermis and of the initiation phase of two-stage tumorigenesis.
The chemotherapeutic agent 6-mercaptopurine was previously shown to inhibit the binding of 7r,8t-dihydroxy-9,10t-oxy-7,8,9,10… 
1985
1985
Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture
Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma… 
1982
1982
Guanosine 5'-monophosphate reductase from Leishmania donovani. A possible chemotherapeutic target.
1982
1982
Antileishmanial action of 4-thiopyrazolo (3.4-d) pyrimidine and its ribonucleoside. Biological effects and metabolism.
1974
1974
Urinary excretion of 6 hydroxylated metabolite and oxypurines in a xanthinuric man given allopurinol or thiopurinol.
Xanthinuria is characterized by a large urinary excretion of oxypurine (xanthine + hypoxanthine) which replaces uric acid at the… 
1974
1974
Thiopurinol and purine metabolism. Metabolic and radioisotope studies.
H. ANNE SIMMONDS*, ANDREW CADENHEAD:, J. STEWART CAMERON*, TREVOR J. RISINGt, RODNEY GRAHAME*, AND BETTY M. DEAN§ From the… 
1974
1974
Metabolic studies of thiopurinol in man and the pig.
Thiopurinol (mercapto-4-pyrazolo (3,4-d) pyrimidine) differs in structure from Allopurinol only by the substitution of a SH… 
1973
1973
Mechanism of antiuric action of 4-oxy- and 4-thiopyrazolopyrimidines.
1968
1968
[Treatment of gouty purine metabolism disorder with mercapto-pyrazolo-pyrimidine (thiopurinol)].
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