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timoprazole

Known as: 2-((2-pyridylmethyl)sulfinyl)benzimidazole 
National Institutes of Health

Related topics

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2 relations

Broader (2)

2-PyridinylmethylsulfinylbenzimidazolesProton Pump Inhibitors

Papers overview

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1998
1998
Gastric transmucosal potential difference: effect of antisecretory and gastroprotective drugs.
1995
1995
Inhibition of thyrocyte iodide uptake by H+K+ ATPase inhibitor, timoprazole.
The inhibitory effect of timoprazole on iodide uptake by cultured thyrocytes was observed using FRTL-5 cells. The inhibition was… 
1991
1991
Studies on (H(+)-K+)-ATPase inhibitors of gastric acid secretion. Prodrugs of 2-[(2-pyridinylmethyl)sulfinyl]benzimidazole proton-pump inhibitors.
The synthesis of N-substituted benzimidazole (H(+)-K+)-ATPase or proton-pump inhibitors is described. These compounds were… 
1987
1987
Surface epithelial cell damage induced by restraint and water-immersion stress in rats effects of 16,16-dimethyl prostaglandin E2 on stress-induced gastric lesions.
The time-course of gastric mucosal surface epithelial cell damage and macroscopically visible lesions in response to restraint… 
1986
1986
Some profiles of transmucosal potential difference in rat stomach determined in situ with special reference to effects of timoprazole, a H+,K+-ATPase inhibitor.
Gastric transmucosal potential difference (PD) is referred to an index of function and integrity of the mucosa. The features of… 
1986
1986
Reduction of rat gastric transmucosal potential difference by indomethacin partly associated with its acid secretory activity.
Gastric transmucosal potential difference (PD) is referred to as an index of function and integrity of the mucosa. Gastric… 
Review
1985
Review
1985
The mechanism of action of omeprazole--a survey of its inhibitory actions in vitro.
In order to study the mechanism of inhibition of gastric acid secretion by omeprazole, its action was investigated in several… 
1984
1984
Timoprazole is a unique cytoprotective agent in the rat.
Timoprazole, a substituted benzimidazole, is an antisecretory agent that inhibits gastric acid secretion by interference with (H… 
Highly Cited
1983
Highly Cited
1983
Effect of substituted benzimidazoles on acid secretion in isolated and enriched guinea pig parietal cells.
The inhibitory effect of the three benzimidazole derivatives timoprazole, picoprazole, and omeprazole on histamine and dbcAMP… 
1983
1983
A micro-method for the study of acid secretory function in isolated human oxyntic glands from gastroscopic biopsies.
1. A method has been developed whereby gastric glands can be obtained from biopsies taken from the human gastric mucosa. 2… 
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