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2-Pyridinylmethylsulfinylbenzimidazoles

Known as: Sulfoxides, Benzimidazole Methylpyridine, 2 Pyridinylmethylsulfinylbenzimidazoles, Benzimidazole Methylpyridine Sulfoxides 
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Here, we describe the identification of a clinical candidate via structure-based optimization of a ligand efficient pyrazole… Expand
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Highly Cited
2009
Highly Cited
2009
  • Shengming Ma
  • Accounts of chemical research
  • 2009
  • Corpus ID: 206830160
Modern organic synthesis depends on the development of highly selective methods for the efficient construction of potentially… Expand
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Highly Cited
2007
Highly Cited
2007
A series of gold(I)-catalyzed rearrangement reactions of alkynyl sulfoxides are reported. Homopropargylsulfoxides are rearranged… Expand
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Highly Cited
2003
Highly Cited
2003
The inhibitive action of some benzimidazole derivatives namely 2-aminobenzimidazole (AB), 2-(2-pyridyl)benzimidazole (PB… Expand
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Highly Cited
2001
Highly Cited
2001
BackgroundFlavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by… Expand
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Highly Cited
1996
Highly Cited
1996
Camptothecin is an S-phase-specific anticancer agent that inhibits the activity of the enzyme DNA topoisomerase-I (topo-I… Expand
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Highly Cited
1996
Highly Cited
1996
Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide… Expand
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Highly Cited
1996
Highly Cited
1996
1. Hippocampal long-term potentiation (LTP) may serve as an elementary process underlying certain forms of learning and memory in… Expand
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Highly Cited
1990
Highly Cited
1990
The primary cytotoxic mechanism of camptothecin has been proposed to involve an interaction between the replication machinery and… Expand
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Highly Cited
1979
Highly Cited
1979
The kinetic constants for the hydrolysis of a series of I-nitroanilide substrates by human leukocyte (HL) elastase and cathepsin… Expand
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