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thymidine catabolic process

Known as: thymidine breakdown, thymidine catabolism, deoxyribosylthymine catabolism 
The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Thymidine Catabolism as a Metabolic Strategy for Cancer Survival.
Thymidine phosphorylase (TP), a rate-limiting enzyme in thymidine catabolism, plays a pivotal role in tumor progression; however… Expand
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2009
2009
Fermentative production of thymidine by a metabolically engineered Escherichia coli strain.
Thymidine is an important precursor in the production of various antiviral drugs, including azidothymidine for the treatment of… Expand
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2007
2007
Mycoplasma in african green monkey kidney cell cultures: Biochemical detection and effects in virus-infected cells
SummaryAmong a number of techniques for the detection of mycoplasmal contamination in African green monkey kidney (AGMK) cell… Expand
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Highly Cited
2000
Highly Cited
2000
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
Thymidine phosphorylase (TP) (E.C. 2.4.2.4), also known as platelet-derived endothelial cell growth factor, is a potent… Expand
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1999
1999
Kinetic analysis of 2-[11C]thymidine PET imaging studies: validation studies.
UNLABELLED 2-[11C]thymidine has been tested as a PET tracer of cellular proliferation. We have previously described a model of… Expand
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1993
1993
Bile acid-induced modifications in DNA synthesis by the regenerating perfused rat liver.
Liver cell proliferation is a complex process that can be affected by a large number of factors such as bile acids, which have… Expand
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1992
1992
Thymidine and 3'-azido-3'-deoxythymidine metabolism in human peripheral blood lymphocytes and monocyte-derived macrophages. A study of both anabolic and catabolic pathways.
3'-Azido-3'-deoxythymidine (AZT) is HIV-inhibitory in human macrophages, which is surprising in view of the low AZT… Expand
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1988
1988
The role of blood platelets in nucleoside metabolism: assay, cellular location and significance of thymidine phosphorylase in human blood.
The enzyme thymidine phosphorylase (thymidine: orthophosphate deoxyribosyltransferase, EC 2.4.2.4), which plays a crucial role in… Expand
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1988
1988
Local and systemic implications of thymidine catabolism by human keratinocytes.
The human epidermis possesses a very active thymidine phosphorylase with the capacity to catabolize all of the thymidine… Expand
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1982
1982
The human blood platelet: a cellular model to study the degradation of thymidine and its inhibition.
Intact platelets catabolize extracellular thymidine into thymine. Studies of the concentration dependent degradation of thymidine… Expand
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