FAQ

thymidine catabolic process

Known as: thymidine breakdown, thymidine catabolism, deoxyribosylthymine catabolism 
The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2017
02419642017

Papers overview

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2009
2009
Fermentative production of thymidine by a metabolically engineered Escherichia coli strain.
Thymidine is an important precursor in the production of various antiviral drugs, including azidothymidine for the treatment of… (More)
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Highly Cited
2000
Highly Cited
2000
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
Thymidine phosphorylase (TP) (E.C. 2.4.2.4), also known as platelet-derived endothelial cell growth factor, is a potent… (More)
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1999
1999
Kinetic analysis of 2-[11C]thymidine PET imaging studies: validation studies.
UNLABELLED 2-[11C]thymidine has been tested as a PET tracer of cellular proliferation. We have previously described a model of… (More)
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1996
1996
[Methyl-carbon-11] thymidine for in vivo measurement of cell proliferation.
UNLABELLED [Methyl-11C]thymidine and PET provide an in vivo, noninvasive, quantitative approach for studying nucleoside uptake in… (More)
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1992
1992
Thymidine and 3'-azido-3'-deoxythymidine metabolism in human peripheral blood lymphocytes and monocyte-derived macrophages. A study of both anabolic and catabolic pathways.
3'-Azido-3'-deoxythymidine (AZT) is HIV-inhibitory in human macrophages, which is surprising in view of the low AZT… (More)
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1991
1991
Elevated thymidine phosphorylase activity in psoriatic lesions accounts for the apparent presence of an epidermal "growth inhibitor," but is not in itself growth inhibitory.
An apparent tissue-specific growth inhibitor, or chalone, obtained from psoriatic lesions was tentatively identified in the 100… (More)
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1988
1988
The role of blood platelets in nucleoside metabolism: assay, cellular location and significance of thymidine phosphorylase in human blood.
The enzyme thymidine phosphorylase (thymidine: orthophosphate deoxyribosyltransferase, EC 2.4.2.4), which plays a crucial role in… (More)
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1988
1988
Effect of 5-fluoro-2'-deoxyuridine on [h]thymidine incorporation by bacterioplankton in the waters of southwest Florida.
The effect of 5-fluoro-2'-deoxyuridine (FdUrd) on [methyl-H] thymidine incorporation by bacterioplankton populations in… (More)
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1982
1982
The human blood platelet: a cellular model to study the degradation of thymidine and its inhibition.
Intact platelets catabolize extracellular thymidine into thymine. Studies of the concentration dependent degradation of thymidine… (More)
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1977
1977
Mycoplasma in african green monkey kidney cell cultures: Biochemical detection and effects in virus-infected cells
Among a number of techniques for the detection of mycoplasmal contamination in African green monkey kidney (AGMK) cell lines, the… (More)
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