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thymidine biosynthetic process
Known as:
thymidine anabolism
, deoxyribosylthymine biosynthesis
, deoxyribosylthymine biosynthetic process
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The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
A second target of benzamide riboside
Breton N. Roussel
,
N. Johnson-Farley
,
+8 authors
J. Bertino
Cancer Biology & Therapy
2012
Corpus ID: 28896132
Dihydrofolate reductase (DHFR) is an essential enzyme involved in de novo purine and thymidine biosynthesis. For several decades…
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2011
2011
Imaging Colon Cancer Response Following Treatment with AZD1152: A Preclinical Analysis of [18F]Fluoro-2-deoxyglucose and 3′-deoxy-3′-[18F]Fluorothymidine Imaging
Maxim A. Moroz
,
Tatiana Kochetkov
,
+9 authors
R. Blasberg
Clinical Cancer Research
2011
Corpus ID: 207691508
Purpose: To determine whether treatment response to the Aurora B kinase inhibitor, AZD1152, could be monitored early in the…
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2004
2004
Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts
F. Buchegger
,
Florence Adamer
,
+6 authors
A. Delaloye
International Journal of Cancer
2004
Corpus ID: 61395
Intratumoural (i.t.) injection of radio‐iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger…
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Highly Cited
2000
Highly Cited
2000
Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy.
M. Koukourakis
,
A. Giatromanolaki
,
G. Fountzilas
,
E. Sivridis
,
K. Gatter
,
Adrian L. Harris
Clinical Cancer Research
2000
Corpus ID: 15607
Thymidine phosphorylase (TP), an enzyme involved in the thymidine synthesis and degradation, has been shown to promote tumor…
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1993
1993
Accumulation of 5‐methyltetrahydrofolic acid and folylpolyglutamate synthetase expression by mitogen stimulated human lymphocytes
D. Fort
,
R. Lark
,
+4 authors
B. Kamen
British Journal of Haematology
1993
Corpus ID: 23970308
Summary. The accumulation of 5‐methyl[3H]tetrahydrofolic acid (5CH3[3H]FH4) by phytohaemagglutinin stimulated lymphocytes (PHA‐L…
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1990
1990
Radiation, pool size and incorporation studies in mice with 5-chloro-2'-deoxycytidine.
O. Santos
,
L. M. Perez
,
T. Briggle
,
D. Boothman
,
S. Greer
International Journal of Radiation Oncology…
1990
Corpus ID: 7311409
Review
1986
Review
1986
Induction of increased salvage pathways of nucleotide synthesis by dosage effect due to chromosome imbalances may be fundamental in carcinogenesis: the example of colorectal carcinoma.
B. Dutrillaux
,
M. Muleris
Annales de Genetique
1986
Corpus ID: 45202831
The cytogenetic study of colorectal carcinomas is consistent with the following sequence in the tumor evolution: rearrangement of…
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1983
1983
Thymidine and Methionine Syntheses in Pregnant Rats Exposed to Nitrous Oxide
J. M. Baden
,
S. Rice
,
M. Serra
,
M. Kelley
,
R. Mazze
Anesthesia and Analgesia
1983
Corpus ID: 41151418
The dose-dependent effects of nitrous oxide on thymidine and methionine syntheses were investigated in pregnant rats. Female…
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Highly Cited
1977
Highly Cited
1977
Biochemical strategy of the genome as expressed in regulation of pyrimidine metabolism.
G. Weber
,
T. Shiotani
,
H. Kizaki
,
D. Tzeng
,
J. Williams
,
N. Gladstone
Advances in Enzyme Regulation
1977
Corpus ID: 44849995
Highly Cited
1969
Highly Cited
1969
The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.
R. Lasher
,
R. Cahn
Developmental Biology
1969
Corpus ID: 20136707
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