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thymidine biosynthetic process

Known as: thymidine anabolism, deoxyribosylthymine biosynthesis, deoxyribosylthymine biosynthetic process 
The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Limits of [18F]-FLT PET as a Biomarker of Proliferation in Oncology
Background Non-invasive imaging biomarkers of cellular proliferation hold great promise for quantifying response to personalized… 
Highly Cited
2010
Highly Cited
2010
Effects of 5-FU.
5-fluorouracil (5-FU) is a chemotherapeutical agent used to treat cancers including breast and colorectal. Working as an… 
2008
2008
Mathematical Modeling of Folate Metabolism: Predicted Effects of Genetic Polymorphisms on Mechanisms and Biomarkers Relevant to Carcinogenesis
Low-folate status and genetic polymorphisms in folate metabolism have been linked to several cancers. Possible biological… 
2008
2008
The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant
Loss of nucleoside diphosphate kinase (Ndk) function in Escherichia coli results in an increased frequency of spontaneous… 
Review
2005
Review
2005
Effects of alcohol on folate metabolism: implications for carcinogenesis.
Highly Cited
2001
Highly Cited
2001
The effect of folic acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro.
We performed a comprehensive study on the genotoxic and cytotoxic effects of in vitro folic acid deficiency on primary human… 
Highly Cited
2000
Highly Cited
2000
Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy.
Thymidine phosphorylase (TP), an enzyme involved in the thymidine synthesis and degradation, has been shown to promote tumor… 
Highly Cited
1997
Highly Cited
1997
Apoptosis and proliferation under conditions of deoxynucleotide pool imbalance in liver of folate/methyl deficient rats.
Weanling male F344 rats were fed either a semi-purified diet low in methionine and lacking in choline and folic acid (folate… 
Highly Cited
1990
Highly Cited
1990
Cyclosporin A suppresses cisplatin-induced c-fos gene expression in ovarian carcinoma cells.
Highly Cited
1969
Highly Cited
1969
The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.
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