thrombin alfa

Known as: thrombin alfa topical, thrombin, recombinant human, recombinant human thrombin 
A recombinant peptide that is chemically identical to or similar to the endogenous thrombin. Thrombin, a serine protease, plays significant roles in… (More)
National Institutes of Health

Papers overview

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2013
2013
BACKGROUND Red blood cell-derived microparticles (RMPs) are small phospholipid vesicles shed from RBCs in blood units, where they… (More)
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2012
2012
INTRODUCTION Edoxaban, an oral direct factor Xa (FXa) inhibitor, is in Phase III development for prevention and treatment of… (More)
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2011
2011
BACKGROUND Despite improved treatment options, myocardial infarction is still an important cause of morbidity and mortality. One… (More)
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2009
2009
BACKGROUND The paucity of organ donors has necessitated redirecting research toward finding alternative means to a heart… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Plasma-derived bovine thrombin is used as a topical agent to improve surgical hemostasis, but development of… (More)
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2003
2003
Pretreatment with a low intracerebral dose of thrombin reduces brain edema after hemorrhagic and thrombo-embolic stroke. We have… (More)
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2003
2003
Factor VIII (FVIII)-bypassing agents have complex modes of action but all control bleeding in inhibitor patients by triggering… (More)
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2000
2000
OBJECTIVE To study the time course of coagulation data in intensive care patients. DESIGN Prospective, descriptive study… (More)
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Highly Cited
1999
Highly Cited
1999
Thrombin generation (TG) initiated by diluted tissue-factor was investigated in whole human blood, in platelet-rich plasma (PRP… (More)
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Review
1992
Review
1992
Nearly all patients with cancer manifest laboratory evidence of hypercoagulability and some develop clinical thromboembolic… (More)
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