Thrombin

Known as: Thrombase, Thrombin [Chemical/Ingredient], fibrinogenase 
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1939-2018
05010015019392017

Papers overview

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Highly Cited
2006
Highly Cited
2006
CONTEXT Screening of patients with venous thromboembolism (VTE) for thrombophilic risk factors is common clinical practice… (More)
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Highly Cited
2002
Highly Cited
2002
Tissue factor-induced blood coagulation was studied in 20 individuals, for varying periods of time during 54 months, in contact… (More)
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Highly Cited
2001
Highly Cited
2001
The heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1) is activated under hypoxic conditions, resulting in the… (More)
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Highly Cited
2000
Highly Cited
2000
Identification of the mechanisms by which the coagulation protease thrombin activates platelets is critical for understanding… (More)
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Highly Cited
2000
Highly Cited
2000
The recent identification of two new thrombin receptors, PAR3 and PAR4, led us to re-examine the basis for endothelial cell… (More)
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Highly Cited
2000
Highly Cited
2000
Thrombin activatable fibrinolysis inhibitor (TAFI, or procarboxypeptidase B) is the precursor of a recently described… (More)
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Highly Cited
1999
Highly Cited
1999
Aberrant regulation of smooth muscle cell proliferation and migration is associated with the pathophysiology of vascular… (More)
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Highly Cited
1996
Highly Cited
1996
Thrombin, a coagulation protease generated at sites of vascular injury, activates platelets, endothelial cells, leukocytes and… (More)
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Highly Cited
1993
Highly Cited
1993
Thrombin has been implicated in the stimulation of smooth muscle cell (SMC) proliferation that contributes to post angioplasty… (More)
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Highly Cited
1992
Highly Cited
1992
Thrombin stimulation of human platelets results in the release of a preformed proteinaceous human eosinophil (Eo)-chemotactic… (More)
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