Thrombin

CONTEXT Screening of patients with venous thromboembolism (VTE) for thrombophilic risk factors is common clinical practice… (More)

Tissue factor-induced blood coagulation was studied in 20 individuals, for varying periods of time during 54 months, in contact… (More)

The heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1) is activated under hypoxic conditions, resulting in the… (More)

Identification of the mechanisms by which the coagulation protease thrombin activates platelets is critical for understanding… (More)

The recent identification of two new thrombin receptors, PAR3 and PAR4, led us to re-examine the basis for endothelial cell… (More)

Thrombin activatable fibrinolysis inhibitor (TAFI, or procarboxypeptidase B) is the precursor of a recently described… (More)

Aberrant regulation of smooth muscle cell proliferation and migration is associated with the pathophysiology of vascular… (More)

Thrombin, a coagulation protease generated at sites of vascular injury, activates platelets, endothelial cells, leukocytes and… (More)

Thrombin has been implicated in the stimulation of smooth muscle cell (SMC) proliferation that contributes to post angioplasty… (More)

Thrombin stimulation of human platelets results in the release of a preformed proteinaceous human eosinophil (Eo)-chemotactic… (More)