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therapeutic autologous dendritic cells

Known as: ADC, autologous dendritic cells 
A population of a type of antigen-presenting cell (APC), the dendritic cell (DC), harvested from a patient and grown in vitro in the presence of… 
National Institutes of Health

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Antigen SensitizationCytotoxic T-LymphocytesNCIt Antineoplastic Agent TerminologyT-Cell Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PF201 THE COMBINATION OF IMGN632, A CD123-TARGETING ADC, WITH VENETOCLAX ENHANCES ANTI-LEUKEMIC ACTIVITY IN VITRO AND PROLONGS SURVIVAL IN VIVO IN PRE-CLINICAL MODELS OF HUMAN AML
2017
2017
Abstract P4-22-15: Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate (ADC) for the treatment of relapsed/refractory, metastatic triple-negative breast cancer (mTNBC…
Background . mTNBC has an aggressive course with limited effective therapy options and a median progression-free survival (PFS… 
2017
2017
Abstract 2630: MEN1309, a novel antibody drug conjugate (ADC) targeting Ly75 antigen, induces complete responses in several xenografts of solid tumors
The cell surface antigen Lymphocyte antigen 75 (LY75, CD205, DEC-205) is over-expressed in several tumor histotypes. It is a type… 
2016
2016
Abstract LB-053: Towards new cryptophycins as promising payloads for ADC
Cryptophycins are a class of macrocyclic depsipeptides produced as secondary metabolites by cyanobacteria of the genus Nostoc and… 
2015
2015
Abstract 5360: The preclinical profile of the duocarmycin-based HER2-targeting ADC SYD985 predicts for clinical benefit in low HER2-expressing breast cancers
SYD985 is a HER2-targeting ADC based on trastuzumab and vc-seco-DUBA, Synthon9s proprietary cleavable linker-duocarmycin payload… 
2010
2010
Abstract 5543: Combining antibody-targeted radiation (radioimmunotherapy) and antibody-SN-38 conjugates (ADC) improves pancreatic cancer therapy
We previously reported effective anti-tumor activity in nude mice bearing human pancreatic tumors with 90 Y-humanized PAM4 IgG… 
2009
2009
Efficacy of immunotherapy using autologous dendritic cells pulsed with hepatitis B surface antigen in patients with chronic hepatitis B
2008
2008
Mcl-1 and anticancer vaccination: identification of an HLA-A2-restricted epitope
The remarkable clinical benefit of donor-lymphocyte infusions as well as the finding that human T cells can destroy chemotherapy… 
2007
2007
Expression of CD 56 by Human Papillomavirus E 7-specific CD 8 + Cytotoxic T Lymphocytes Correlates with Increased Intracellular Perforin Expression and Enhanced Cytotoxicity against HLA-A 2-matched…
  • 2007
  • Corpus ID: 35525939
H u m a n papi l lomavirus (HPV) infection represents the most impor t an t r isk factor for developing cervical cancer. In this… 
1999
1999
Major Histocompatibility Complex Class I Restricted Cytotoxic T Cells Specific for Natural Melanoma Peptides Recognize Unidentified Shared Melanoma Antigen ( s ) 1
CTLs were generatedin vitro from two healthy donors and one melanoma patient by stimulation of CD8 T cells with autologous…