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This study describes an investigation of the thermospray (TS) mass spectrometric analysis of tripelennamine, methapyrilene… Expand The possibility was examined that the induction of tumors in rat liver by feeding methapyrilene, which is not mutagenic, is… Expand The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine… Expand 1. Strains of the fungus Cunninghamella elegans ATCC 9245 and 36112 were tested for their ability to transform the antihistamines… Expand Methapyrilene and four related antihistamines were evaluated for their ability to cause DNA repair measured autoradiographically… Expand 8 drugs that are amines or amides and that interact with nitrous acid to form potentially carcinogenic and mutagenic N-nitroso… Expand Bronchoconstriction was induced in nonsensitized dogs by intravenous injections of soluble immune complexes. Immune complex… Expand Several bronchoconstrictor and smooth muscle relaxant agents were studied in a dog preparation (in vivo) and on guinea pig… Expand Twenty-one hypertensive asthmatic patients received two inhalations of isoetharine compound in pressurized aerosol form (from a… Expand Isoetharine (Dilabron) is 1-(3,4-dihydroxyphenyl)-2-isopropylamino-1-butanol HCl. This drug is a potent bronchodilator agent… Expand