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tetrahydroneopterin

Known as: 2-amino-5,6,7,8-tetrahydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone, 5,6,7,8-tetrahydroneopterin 
 
National Institutes of Health

Papers overview

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2013
2013
BackgroundIncreased levels of the sugar metabolite methylglyoxal (MG) in vivo were shown to participate in the pathophysiology of… Expand
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Highly Cited
2010
Highly Cited
2010
Background— Heart failure with preserved ejection fraction is 1 consequence of hypertension and is caused by impaired cardiac… Expand
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Highly Cited
2008
Highly Cited
2008
Recently generated caveolin-1 deficient mice (cav-1(-/-)) display several physiological alterations such as severe heart failure… Expand
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Highly Cited
2005
Highly Cited
2005
Cardiac pressure load stimulates hypertrophy, often leading to chamber dilation and dysfunction. ROS contribute to this process… Expand
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Highly Cited
2000
Highly Cited
2000
Conditions associated with impaired nitric oxide (NO) activity and accelerated atherosclerosis have been shown to be associated… Expand
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1993
1993
The protective effect of the reduced form of neopterin, 5,6,7,8-tetrahydroneopterin (NPH4), against the cardiotoxicity of… Expand
Highly Cited
1992
Highly Cited
1992
The in vitro potency of neopterin (NP) as an antioxidant and its in vivo activity to suppress alloxan‐induced diabetes were… Expand
Highly Cited
1990
Highly Cited
1990
Previously we described a new form of human hyperphenylalaninemia characterized by the formation of 7-substituted pterins. We… Expand
Highly Cited
1980
Highly Cited
1980
Abstract A reverse-phese high-performance liquid chromatography (hplc) procedure was developed for the separation of biopterin… Expand
1969
1969
Abstract The stability of tetrahydropterins to oxidation has been investigated. Oxidation products, pterin and… Expand