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tetrahydroneopterin

Known as: 2-amino-5,6,7,8-tetrahydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone, 5,6,7,8-tetrahydroneopterin 
 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Heart failure with preserved ejection fraction is 1 consequence of hypertension and is caused by impaired cardiac… Expand
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2008
2008
Recently generated caveolin-1 deficient mice (cav-1(-/-)) display several physiological alterations such as severe heart failure… Expand
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Highly Cited
2005
Highly Cited
2005
Cardiac pressure load stimulates hypertrophy, often leading to chamber dilation and dysfunction. ROS contribute to this process… Expand
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Highly Cited
2000
Highly Cited
2000
Conditions associated with impaired nitric oxide (NO) activity and accelerated atherosclerosis have been shown to be associated… Expand
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1995
1995
Neopterin is an 2-amino-4-hydroxypteridine derivative and a precursor of biopterin, which is derived from guanosine triphosphate… Expand
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1993
1993
The protective effect of the reduced form of neopterin, 5,6,7,8-tetrahydroneopterin (NPH4), against the cardiotoxicity of… Expand
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1993
1993
The therapeutic potency of 5,6,7,8-tetrahydroneopterin (NPH4) was investigated in ischemic paw edema, Adriamycin (ADR)-induced… Expand
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1992
1992
The in vitro potency of neopterin (NP) as an antioxidant and its in vivo activity to suppress alloxan-induced diabetes were… Expand
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Highly Cited
1984
Highly Cited
1984
A 4-year-old patient is described with hyperphenylalaninemia, severe retardation in development, severe muscular hypotonia of the… Expand
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Highly Cited
1980
Highly Cited
1980
Abstract A reverse-phese high-performance liquid chromatography (hplc) procedure was developed for the separation of biopterin… Expand
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