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tetrahydrobiopterin biosynthetic process

Known as: tetrahydrobiopterin formation, tetrahydrobiopterin synthesis, tetrahydrobiopterin biosynthesis 
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2… 
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
Human epidermal melanocytes and keratinocytes express mRNA for all enzymes involved in de novo synthesis/recycling of the… 
1998
1998
The purpose of this study was to examine the effect of tetrahydrobiopterin, a co-factor of nitric oxide synthase, on H2O2-induced… 
1996
1996
Nitric oxide synthesis requires the cofactor tetrahydrobiopterin. We have examined the effect on nitric oxide synthesis in… 
Highly Cited
1996
Highly Cited
1996
Abstract: hph‐1 mice, which have defective tetrahydrobiopterin biosynthesis due to decreased GTP cyclohydrolase I activity, have… 
1994
1994
Endotoxin and inflammatory cytokines downregulate expression of constitutive nitric oxide synthase (cNOS) in human vascular… 
Highly Cited
1993
Highly Cited
1993
Endothelial cells, through soluble mediators, play an important role in the regulation of the vascular tone. In the present paper… 
Highly Cited
1982
Highly Cited
1982
Substantial amounts of tetrahydrobiopterin and 6-methyltetrahydropterin can be detected in CSF when these pterins are given…