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tesmilifene
Known as:
DEPMPE
, DPPE
, N,N-diethyl-2-(4-(phenylmethyl)phenoxy)ethanamine
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National Institutes of Health
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Related topics
Related topics
5 relations
Broader (3)
Histamine Antagonists
Phenyl Ethers
Platelet Aggregation Inhibitors
cyclophosphamide/tesmilifene
doxorubicin/tesmilifene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Origin of the ligand effect in the cobalt catalyzed regioselective hydroboration of 1,3-diene.
Yuhua Liu
,
ZhongJie Jiang
,
Jipei Chen
Organic and biomolecular chemistry
2020
Corpus ID: 218506656
Hydroboration of 1,3-dienes can provide useful intermediates with multiple functionalities. However, achieving high…
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2010
2010
Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P‐glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats
Young H. Choi
,
J. H. Suh
,
Joo H. Lee
,
I. Cho
,
Myung G. Lee
The Journal of pharmacy and pharmacology
2010
Corpus ID: 719197
Objectives It has been reported that docetaxel is a P‐glycoprotein substrate and is metabolized via the cytochrome P450 (CYP) 3A…
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2009
2009
Preferential Killing of Breast Tumor Initiating Cells by N,N-Diethyl-2-[4-(Phenylmethyl)Phenoxy]Ethanamine/Tesmilifene
T. Deng
,
Jeffrey C. Liu
,
K. Pritchard
,
A. Eisen
,
E. Zacksenhaus
Clinical Cancer Research
2009
Corpus ID: 30855551
Purpose:N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE; tesmilifene) is thought to potentiate the antineoplastic effect…
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2009
2009
Enhancement of cytotoxicity of natural product drugs against multidrug resistant variant cell lines of human head and neck squamous cell carcinoma and breast carcinoma by tesmilifene.
P. Ferguson
,
A. Brisson
,
J. Koropatnick
,
M. Vincent
Cancer Letters
2009
Corpus ID: 9218857
2008
2008
Electrophoresis of membrane-associated molecules in packed beds of bilayer-coated particles.
Kenji. Suzuki
,
K. Hosokawa
,
M. Maeda
Journal of the American Chemical Society
2008
Corpus ID: 207046698
We describe a new method for large-scale separation of membrane-associated biomolecules using a packed bed of bilayer-coated…
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2008
2008
N,N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine (DPPE; tesmilifene), a chemopotentiating agent with hormetic effects on DNA synthesis in vitro, may improve survival in patients with metastatic…
L. Brandes
Human and Experimental Toxicology
2008
Corpus ID: 20966915
N,N -diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine (DPPE; tesmilifene) is a novel anti-histaminic and chemopotentiating agent…
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2008
2008
Prostate cancer: moving forward by reinventing the wheel...but this time it is round.
D. Raghavan
,
E. Klein
Journal of Clinical Oncology
2008
Corpus ID: 38219290
The article by Attard et al in this issue of Journal of Clinical Oncology illustrates elegantly that we are gradually coming to…
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2007
2007
The phospholipidosis-lnducing potential of the chemopotentiating drug, N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene) correlates with its stimulation of phosphatidylserine…
Fred Y. Xu
,
G. Queen
,
L. Brandes
,
G. Hatch
Proceedings of the Western Pharmacology Society
2007
Corpus ID: 21372415
N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene), a potent chemopotentiating drug currently in Phase III…
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2005
2005
Subgroup analysis of a phase III trial of doxorubicin vs doxorubicin plus tesmilifene in advanced breast cancer (ABC): Tesmilifene survival benefit focused on patients with more aggressive disease
M. Vincent
,
P. Keane
,
H. Chen
,
K. Pritchard
2005
Corpus ID: 56589466
756 Background: Tesmilifene (DPPE), a novel chemopotentiating small molecule, conferred a substantial (50%+) increase in median…
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2005
2005
Biological Effects of Low Level Exposures BIOMEDICAL IMPLICATIONS OF HORMESIS – PART 1 TABLE OF CONTENTS
Wayne B. Jonas
2005
Corpus ID: 264834924
The idea that low-dose adaptive effects as described in hormesis can be used clinically has been discussed for hundreds if not…
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