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Rapid aggregation of gold nanoparticles induced by non-cross-linking DNA hybridization.
TLDR
This non-cross-linking aggregation system for 15 nm diameter gold nanoparticles functionalized with (alkanethiol)-15mer DNA opens up a new possibility of rapid and reliable genetic analysis. Expand
Scaffolds from electrospun polyhydroxyalkanoate copolymers: fabrication, characterization, bioabsorption and tissue response.
TLDR
The tissue response was found to improve with the high content of 4-hydroxybutyrate and the content and type of the second monomer and the diameter of fiber significantly influence the bioabsorption. Expand
Power-free poly(dimethylsiloxane) microfluidic devices for gold nanoparticle-based DNA analysis.
TLDR
An extremely simple, power-free pumping method for poly(dimethylsiloxane)(PDMS) microfluidic devices is presented, and gold nanoparticle-based DNA analysis, which does not rely on the cross-linking mechanism between nanoparticles, has been implemented in a microchannel with three inlets. Expand
Non-cross-linking gold nanoparticle aggregation as a detection method for single-base substitutions
TLDR
Aggregation of DNA-modified gold nanoparticles in a non-cross-linking configuration has extraordinary selectivity against terminal mismatch of the surface-bound duplex, which opens up a new possibility of point-of-care diagnosis for single-nucleotide polymorphisms. Expand
FRET-based monitoring of conformational change of the beta2 adrenergic receptor in living cells.
TLDR
Monitoring of an agonist-induced conformational change of beta(2)AR in living cells indicates that the ICL3 approached the C-terminus upon activation, similar to that of the norepinephrine-responsive alpha(2A) adrenergic receptor reported recently. Expand
Motif CXCC in nitrile hydratase activator is critical for NHase biogenesis in vivo
TLDR
Findings suggest NHase activator mainly participates in iron trafficking in NHase biogenesis as an iron type metallochaperone. Expand
Prefoldin Protects Neuronal Cells from Polyglutamine Toxicity by Preventing Aggregation Formation*
TLDR
In vitro single molecule observation demonstrated that prefoldin suppressed HTT aggregation at the small oligomer (dimer to tetramer) stage, and suggest that soluble oligomers of polyQ-expanded HTT are more toxic than are inclusion to cells. Expand
Photoinduced Hydrogen Production by Direct Electron Transfer from Photosystem I Cross-Linked with Cytochrome c3 to [NiFe]-Hydrogenase
TLDR
To establish an H2 photoproduction system in which the activity is not interrupted by Fd and FNR, position 40 of PsaE from Synechocystis sp. Expand
Core-shell structure, biodegradation, and drug release behavior of poly(lactic acid)/poly(ethylene glycol) block copolymer micelles tuned by macromolecular stereostructure.
TLDR
As indicated by the synchrotron radiation small-angle X-ray scattering results, the stereoblock copolymer micelles have larger size, micellar aggregation number, core radius, smaller core density, and looser packing of core-forming segments than the isotactic and enantiomerically-mixed copolymers. Expand
DNA-responsive hydrogels that can shrink or swell.
TLDR
Novel hybrid hydrogels containing rationally designed ssDNA as the cross-linker were capable of shrinking or swelling in response to ssDNA samples and recognizing a single base difference in the samples. Expand
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