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taxane 10-beta-hydroxylase activity

Known as: taxane 10b-hydroxylase activity, taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating), 5-alpha-taxadienol-10-beta-hydroxylase activity 
Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O… 
National Institutes of Health

Papers overview

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2019
2019
Effect of Exercise on Taxane Chemotherapy-Induced Peripheral Neuropathy in Women With Breast Cancer: A Randomized Controlled Trial.
Review
2017
Review
2017
Developments and future clinical outlook of taxane nanomedicines.
2017
2017
Anti-Müllerian hormone (AMH) levels in premenopausal breast cancer patients treated with taxane-based adjuvant chemotherapy - A translational research project of the SUCCESS A study.
2013
2013
Sciadopitysin: active component from Taxus chinensis for anti-Alzheimer's disease
Five taxane diterpenoids derived from the 95% ethanol extract of Taxus chinensis were tested for the inhibitory activities on… 
Highly Cited
2005
Highly Cited
2005
The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.
Review
2004
Review
2004
Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase.
2002
2002
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Taxane-based therapies appear to have a significant efficacy in clinical trials on hormone-refractory prostate carcinoma. In the… 
2001
2001
Biotransformation of a 4(20),11(12)-taxadiene derivative.
Highly Cited
2000
Highly Cited
2000
A differential scanning calorimetry study of phosphocholines mixed with paclitaxel and its bromoacylated taxanes.
1991
1991
Taxinine M, a new tetracyclic taxane from Taxus brevifolia.
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