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taxane 10-beta-hydroxylase activity

Known as: taxane 10b-hydroxylase activity, taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating), 5-alpha-taxadienol-10-beta-hydroxylase activity 
Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O… 
National Institutes of Health

Papers overview

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2005
2005
A prominent mechanism of drug resistance to taxanes is the overexpression of class III B-tubulin. The seco-taxane IDN5390 was… 
2003
2003
Platycodon grandiflorum cell suspension cultures were employed to biotransform the taxane diterpenoids 2 f ,5 f , 10 g ,14 g… 
2002
2002
Three new C-14 oxygenated taxane-type diterpenes, hongdoushans A-C (1-3), were isolated from the wood of Taxus yunnanensis… 
2002
2002
Five new taxane diterpenoids, taxumairols G (1), H (2), I (3), J (4), and L (5) were isolated from extracts of the roots of… 
1990
1990
Two new taxane diterpenes, decinnamoyltaxagifine ( 3) and decinnanioyltaxagifine acetate ( 2), have been isolated from the leaves…