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talsupram

 
National Institutes of Health

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Papers overview

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2007
2007
Noradrenergic Mechanisms in Cocaine-Induced Reinstatement of Drug Seeking in Squirrel Monkeys
Norepinephrine (NE) uptake and NE receptor mechanisms play important modulating roles in the discriminative stimulus and… Expand
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2005
2005
Effect of imipramine in the “learned helplessness” model of depression in rats is not mimicked by combinations of specific reuptake inhibitors and scopolamine
Administration of imipramine, which blocks noradrenergic, serotonergic and cholinergic reuptake, to rats for 4 days counteracts… Expand
  • figure 1
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2004
2004
Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.
PET and SPECT ligands for the norepinephrine transporter (NET) will be important tools for studying the physiology… Expand
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2003
2003
Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test
The rat forced swim test (FST) is a model that is used extensively as a screening test for antidepressant activity. It has… Expand
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Review
2003
Review
2003
Chapter 29. A Model System for Studying the Role of Dopamine in the Prefrontal Cortex during Early Development in Humans: Early and Continuously Treated Phenylketonuria
After a brief overview of the anatomy of dorsolateral prefrontal cortex (DL-PFC) and of its anatomical connections with other… Expand
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1997
1997
Discriminative stimulus effects of magnesium chloride: substitution studies with monoamine uptake inhibitors and N-methyl-D-aspartate antagonists.
Previous studies suggest that magnesium chloride may have discriminative stimulus effects that partially overlap with those of… Expand
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Highly Cited
1995
Highly Cited
1995
Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys.
  • Roger D. Spealman
  • The Journal of pharmacology and experimental…
  • 1995
    • Corpus ID: 36360974
Noradrenergic involvement in the discriminative stimulus (DS) effects of cocaine was investigated in squirrel monkeys by using a… Expand
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1995
1995
[3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum.
Caudate-putamen membranes of rhesus monkey were solubilized (1% digitonin; w/v) and [3H]WIN 35,428 ([3H]CFT: 2 beta-carbomethoxy… Expand
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1987
1987
Role of brain monoaminergic systems in the increased ethanol drinking caused by REM-sleep deprivation.
The central monoaminergic neuronal effects of REM-sleep deprivation, and the effect of different monoamine uptake blocking agents… Expand
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1986
1986
REM-sleep deprivation-induced increase in ethanol intake: role of brain monoaminergic neurons.
The ethanol intake of Long-Evans male rats was recorded before, during and after deprivation of rapid eye movement (REM) sleep… Expand
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