talabostat

Known as: [(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid, valinyl-boroproline 
A small molecule with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat… (More)

Topic mentions per year

Topic mentions per year

2006-2018
02420062018

Papers overview

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2016
2016
OBJECTIVE Fibroblast activation protein (FAP) is a serine protease belonging to a S9B prolyl oligopeptidase subfamily. This… (More)
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2011
2011
Fibroblast activation protein-α (FAP) is a cell surface, serine protease of the post-prolyl peptidase family that is expressed in… (More)
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2009
2009
AIMS Currently available therapies do improve survival in advanced stage non-small cell lung cancer (NSCLC), but only to a… (More)
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2008
2008
Metastatic melanoma is an incurable disease with an average survival of less than one year. Talabostat is a novel dipeptidyl… (More)
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2008
2008
Selection of potent yet low reactogenic adjuvants for protein immunization is important for HIV-1 vaccine development… (More)
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2007
2007
PURPOSE Fibroblast Activation Protein (FAP) is a tumor fibroblast protease that has been shown to potentiate colorectal cancer… (More)
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Review
2007
Review
2007
Talabostat mesilate is an orally active, specific inhibitor of dipeptidyl peptidases, including tumor-associated fibroblast… (More)
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2006
2006
8040 Background: Talabostat (TAL) is an oral inhibitor of dipeptidyl peptidases such as fibroblast activation protein found on… (More)
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2006
2006
6598 Background: Talabostat (TAL) is an orally administered small molecule inhibitor of dipeptidyl peptidases such as CD26 and… (More)
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2006
2006
9009 Background: Dipeptidyl peptidases comprise a family of serine proteases that includes the genes dipeptidyl peptidase IV (DPP… (More)
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