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Dipeptides

Known as: Dipeptides [Chemical/Ingredient], dipeptide 
Peptides composed of two amino acid units.
National Institutes of Health

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2-N-carbobenzylglycylglycylamido-5-bromobenzophenone4-hydroxybenzoylglycylphenylalanineA 53868AAEG 40730
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antagonists & inhibitors

Papers overview

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Review
2017
Review
2017
Amyloid beta: structure, biology and structure-based therapeutic development
Amyloid beta peptide (Aβ) is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein… Expand
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Review
2017
Review
2017
The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
Expansion of a hexanucleotide (GGGGCC) repeat in the gene chromosome 9 open reading frame 72 (C9ORF72) is the most common cause… Expand
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Review
2016
Review
2016
Peptide self-assembly: thermodynamics and kinetics.
Self-assembling systems play a significant role in physiological functions and have therefore attracted tremendous attention due… Expand
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Highly Cited
2013
Highly Cited
2013
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Expansion of a GGGGCC hexanucleotide repeat upstream of the C9orf72 coding region is the most common cause of familial… Expand
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Highly Cited
2004
Highly Cited
2004
Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics…
Computational studies of proteins based on empirical force fields represent a powerful tool to obtain structure-function… Expand
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Highly Cited
2003
Highly Cited
2003
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection.
Nod2 activates the NF-kappaB pathway following intracellular stimulation by bacterial products. Recently, mutations in Nod2 have… Expand
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Highly Cited
2003
Highly Cited
2003
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease.
NOD2, a protein associated with susceptibility to Crohn's disease, confers responsiveness to bacterial preparations of… Expand
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Highly Cited
2003
Highly Cited
2003
A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations
Molecular mechanics models have been applied extensively to study the dynamics of proteins and nucleic acids. Here we report the… Expand
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Highly Cited
2003
Highly Cited
2003
Structure validation by Calpha geometry: phi,psi and Cbeta deviation.
Geometrical validation around the Calpha is described, with a new Cbeta measure and updated Ramachandran plot. Deviation of the… Expand
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Highly Cited
1998
Highly Cited
1998
All-atom empirical potential for molecular modeling and dynamics studies of proteins.
New protein parameters are reported for the all-atom empirical energy function in the CHARMM program. The parameter evaluation… Expand
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