PT-100 dipeptide

Known as: ((2R)-1-((2S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic Acid Methanesulfonate, Talabostat Mesylate, Val-boro-Pro 
The mesylate salt of an orally active small molecule with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2009
0120032009

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2009
2009
AIMS Currently available therapies do improve survival in advanced stage non-small cell lung cancer (NSCLC), but only to a… (More)
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Review
2007
Review
2007
Talabostat mesilate is an orally active, specific inhibitor of dipeptidyl peptidases, including tumor-associated fibroblast… (More)
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2006
2006
3594 Background: Fibroblast activation protein (FAP) is selectively expressed by carcinoma stromal fibroblasts, but not by… (More)
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2004
2004
The amino boronic dipeptide, PT-100 (Val-boro-Pro), a dipeptidyl peptidase (DPP) inhibitor, has been shown to up-regulate gene… (More)
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2003
2003
In hematopoiesis, cytokine levels modulate blood cell replacement, self-renewal of stem cells, and responses to disease. Feedback… (More)
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