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tachpyr

Known as: N,N',N''-tris(2-pyridylmethyl)-cis,cis-1,3,5-triaminocyclohexane, tachpyridine, tachypyridine 
National Institutes of Health

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2 relations

Broader (2)

CyclohexylaminesPyridines

Papers overview

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2005
2005
Preliminary evaluation of the cytotoxicity of a series of tris-2-aminoethylamine (Tren) based hexadentate heterocyclic donor agents.
Highly Cited
2004
Highly Cited
2004
Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelator.
2004
2004
Synthesis and potent antitumor activities of novel 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives.
The iron chelator N,N',N' '-tris(2-pyridylmethyl)-cis,cis-1,3,5-triaminocyclohexane (tachpyr) was recently reported to display… 
2004
2004
Nickel(II), copper(II) and zinc(II) binding properties and cytotoxicity of tripodal, hexadentate tris(ethylenediamine)--analogue chelators.
Three tripodal hexamine chelators based on cis,cis-1,3,5-triaminocyclohexane (tach) have been synthesized and their aqueous… 
2003
2003
Evaluation of copper chelation agents as anti-angiogenic therapy.
Review
2002
Review
2002
Novel chelating agents for potential clinical applications of copper.
2002
2002
Copper(II)-cis,cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides: kinetic, speciation and structural studies
Abstract. The hydrolysis of glycylglycine (GylGly), glycyl-L-leucine (GlyLeu), L-leucylglycine (LeuGly) and glycyl-DL-serine… 
2001
2001
Novel cytotoxic chelators that bind iron(II) selectively over zinc(II) under aqueous aerobic conditions.
To achieve cellular iron deprivation by chelation, it is important to develop chelators with selective metal-binding properties… 
1998
1998
Novel iron complexes and chelators based on cis,cis-1,3,5-triaminocyclohexane: iron-mediated ligand oxidation and biochemical properties
Abstract The interaction of Fe(II) and Fe(III) with the novel Fe(II) chelator N,N′N″-tris(2-pyridylmethyl)-cis,cis-1,3,5… 
1997
1997
Tricationic Metal Complexes ([ML][NO(3)](3), M = Ga, In) of N,N',N"-Tris(2-pyridylmethyl)- cis-1,3,5-triaminocyclohexane: Preparation and Structure.
The novel hexadentate chelator tachpy, composed of the cis-1,3,5-triaminocyclohexane framework with N-pendant 2-pyridylmethyl… 
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