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tachpyr

Known as: N,N',N''-tris(2-pyridylmethyl)-cis,cis-1,3,5-triaminocyclohexane, tachpyridine, tachypyridine 
National Institutes of Health

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2 relations

Broader (2)

CyclohexylaminesPyridines

Papers overview

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2005
2005
Preliminary evaluation of the cytotoxicity of a series of tris-2-aminoethylamine (Tren) based hexadentate heterocyclic donor agents.
Highly Cited
2004
Highly Cited
2004
Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelator.
2004
2004
Synthesis and potent antitumor activities of novel 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives.
The iron chelator N,N',N' '-tris(2-pyridylmethyl)-cis,cis-1,3,5-triaminocyclohexane (tachpyr) was recently reported to display… 
2003
2003
Evaluation of copper chelation agents as anti-angiogenic therapy.
Highly Cited
2002
Highly Cited
2002
Activation of Caspase Pathways during Iron Chelator-mediated Apoptosis*
Iron chelators have traditionally been used in the treatment of iron overload. Recently, chelators have also been explored for… 
Review
2002
Review
2002
Novel chelating agents for potential clinical applications of copper.
2002
2002
Copper(II)-cis,cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides: kinetic, speciation and structural studies
Abstract. The hydrolysis of glycylglycine (GylGly), glycyl-L-leucine (GlyLeu), L-leucylglycine (LeuGly) and glycyl-DL-serine… 
2002
2002
Mechanisms underlying the cytotoxic effects of Tachpyr--a novel metal chelator.
1998
1998
Novel iron complexes and chelators based on cis,cis-1,3,5-triaminocyclohexane: iron-mediated ligand oxidation and biochemical properties
Abstract The interaction of Fe(II) and Fe(III) with the novel Fe(II) chelator N,N′N″-tris(2-pyridylmethyl)-cis,cis-1,3,5… 
1997
1997
Tricationic Metal Complexes ([ML][NO(3)](3), M = Ga, In) of N,N',N"-Tris(2-pyridylmethyl)- cis-1,3,5-triaminocyclohexane: Preparation and Structure.
The novel hexadentate chelator tachpy, composed of the cis-1,3,5-triaminocyclohexane framework with N-pendant 2-pyridylmethyl… 
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