Cyclohexylamines

Known as: Cyclohexylamine, Cyclohexylamines [Chemical/Ingredient] 
A family of alicyclic hydrocarbons containing an amine group with the general formula R-C6H10NH2.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
0102019492017

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Narrower (43)

1,2-cyclohexanediamine1,3,5-triaminocyclohexane1,4-bis(aminocyclohexyl)methane1,4-diaminocyclohexane
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In Bloodagonistsantagonists & inhibitorsaspects of radiation effects
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Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Cyclohexylamines
standards characteristics
chemical synthesis
1,2-cyclohexanediamine
shinorine
Cyclohexylamine (substance)

Papers overview

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2002
2002
2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex.
cis-trans-cis-Ammine(cyclohexylamine)diacetatodichloroplatinum(IV) is an oral analog of the platinum anti-cancer drug cisplatin… (More)
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Highly Cited
2001
Highly Cited
2001
Equilibrium Acidities in Dimethyl Sulfoxide Solution
The first acidity scale to be established in a pure solvent other than water was the result of the pioneering work of Conant… (More)
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2000
2000
Pharmacokinetic and pharmacodynamic analysis of bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) administered once a day for five consecutive days: a phase I study.
BACKGROUND Bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) is the first orally given platinum complex that shows… (More)
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Highly Cited
1999
Highly Cited
1999
Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts.
Tumors exhibit a spectrum of cellular responses to chemotherapy ranging from extreme sensitivity to resistance, either intrinsic… (More)
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1999
1999
Biodegradation of cyclohexylamine by Brevibacterium oxydans IH-35A.
A bacterial strain capable of growing on cyclohexylamine (CHAM) was isolated by using enrichment and isolation techniques. The… (More)
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1994
1994
Schedule dependency of orally administered bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) in vivo.
JM216 is a novel antitumor platinum(IV) complex displaying oral activity, dose-limiting myelosuppression, and a lack of nephro… (More)
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Highly Cited
1993
Highly Cited
1993
Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.
The cytotoxicity of a novel platinum(IV) complex, bis-acetato-amminedichloro-cyclohexylamine platinum(IV) (JM216), has been… (More)
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1989
1989
The pharmacokinetics and tissue concentrations of cyclohexylamine in rats and mice.
Cyclohexylamine showed dose-dependent kinetics after administration of single oral doses up to 500 mg/kg in rats, with a… (More)
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1970
1970
Bladder tumors in rats fed cyclohexylamine or high doses of a mixture of cyclamate and saccharin.
Papillary transitional cell tumors were found in the urinary bladders in 8 rats out of 80 that received 2600 milligrams per… (More)
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1969
1969
Cytogenetic studies in rats of cyclohexylamine, a metabolite of cyclamate.
Cyclohexylamine, the major known metabolite of cyclamate, was tested in vivo for possible cytogenetic effects. In rats injected… (More)
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