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t(1;19)

A cytogenetic abnormality that involves a translocation between chromosomes 1 and 19.
National Institutes of Health

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2 relations
Chromosomes, Human, Pair 1Chromosomes, Human, Pair 19

Papers overview

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Highly Cited
2009
Highly Cited
2009
Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1
To evaluate the impact of contemporary therapy on the clinical outcome of children with pre-B acute lymphoblastic leukemia (ALL… 
Highly Cited
2006
Highly Cited
2006
A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma.
Combined deletion of chromosomes 1p and 19q is associated with improved prognosis and responsiveness to therapy in patients with… 
Review
2006
Review
2006
Chromatin structural elements and chromosomal translocations in leukemia.
Review
1999
Review
1999
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD… 
Highly Cited
1991
Highly Cited
1991
The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
The t(1;19) translocation that characterizes 25% of pediatric pre-B cell acute lymphoblastic leukemias (pre-B ALL) produces a… 
Highly Cited
1990
Highly Cited
1990
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all
Highly Cited
1990
Highly Cited
1990
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
Highly Cited
1990
Highly Cited
1990
Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study
The prognostic significance of chromosomal translocations, particularly t(1;19) (q23;p13), was evaluated in children with pre-B… 
Highly Cited
1989
Highly Cited
1989
The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias.
The gene (E2A) that codes for proteins with the properties of immunoglobulin enhancer binding factors E12/E47 was mapped to… 
Highly Cited
1984
Highly Cited
1984
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia
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