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t(1;19)
A cytogenetic abnormality that involves a translocation between chromosomes 1 and 19.
National Institutes of Health
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2 relations
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 19
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Highly Cited
2009
Highly Cited
2009
Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1
S. Jeha
,
D. Pei
,
+11 authors
C. Pui
Leukemia
2009
Corpus ID: 25333393
To evaluate the impact of contemporary therapy on the clinical outcome of children with pre-B acute lymphoblastic leukemia (ALL…
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Highly Cited
2006
Highly Cited
2006
A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma.
R. Jenkins
,
H. Blair
,
+9 authors
J. Buckner
Cancer Research
2006
Corpus ID: 9435705
Combined deletion of chromosomes 1p and 19q is associated with improved prognosis and responsiveness to therapy in patients with…
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Review
2006
Review
2006
Chromatin structural elements and chromosomal translocations in leukemia.
Yanming Zhang
,
J. Rowley
DNA Repair
2006
Corpus ID: 1504618
Review
1999
Review
1999
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
J. V. Dongen
,
E. Macintyre
,
+14 authors
A. Biondi
Leukemia
1999
Corpus ID: 538964
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD…
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Highly Cited
1991
Highly Cited
1991
The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
M. Kamps
,
A. Look
,
D. Baltimore
Genes & Development
1991
Corpus ID: 27691206
The t(1;19) translocation that characterizes 25% of pediatric pre-B cell acute lymphoblastic leukemias (pre-B ALL) produces a…
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Highly Cited
1990
Highly Cited
1990
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all
M. Kamps
,
C. Murre
,
Xiao-Hong Sun
,
D. Baltimore
Cell
1990
Corpus ID: 39661371
Highly Cited
1990
Highly Cited
1990
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
J. Nourse
,
J. Mellentin
,
+4 authors
M. Cleary
Cell
1990
Corpus ID: 7975269
Highly Cited
1990
Highly Cited
1990
Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study
W. Crist
,
A. Carroll
,
+7 authors
D. Pullen
1990
Corpus ID: 208197866
The prognostic significance of chromosomal translocations, particularly t(1;19) (q23;p13), was evaluated in children with pre-B…
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Highly Cited
1989
Highly Cited
1989
The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias.
J. Mellentin
,
C. Murre
,
+6 authors
M. Cleary
Science
1989
Corpus ID: 7217862
The gene (E2A) that codes for proteins with the properties of immunoglobulin enhancer binding factors E12/E47 was mapped to…
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Highly Cited
1984
Highly Cited
1984
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia
DorothyL. Williams
,
A. Look
,
+4 authors
S. Stass
Cell
1984
Corpus ID: 25902294
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