t(1;19)

A cytogenetic abnormality that involves a translocation between chromosomes 1 and 19.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
We report that t(1;19) ALL cells universally exhibit expression of and dependence on the cell surface receptor ROR1. We further… (More)
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Highly Cited
2006
Highly Cited
2006
Combined deletion of chromosomes 1p and 19q is associated with improved prognosis and responsiveness to therapy in patients with… (More)
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Highly Cited
2005
Highly Cited
2005
The Wnt family of secreted glycoproteins is widely involved in cell proliferation, differentiation and oncogenesis. Many Wnt… (More)
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Review
1999
Review
1999
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD… (More)
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Highly Cited
1991
Highly Cited
1991
The t(1;19) translocation that characterizes 25% of pediatric pre-B cell acute lymphoblastic leukemias (pre-B ALL) produces a… (More)
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Highly Cited
1990
Highly Cited
1990
It was previously shown that the chromosome 19 breakpoint of the t(1;19)(q23;p13.3) translocation, found in human pre-B cell… (More)
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Highly Cited
1990
Highly Cited
1990
The gene (E2A) for enhancer binding transcription factors E12 and E47 maps to the t(1;19) chromosomal translocation breakpoint in… (More)
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Highly Cited
1990
Highly Cited
1990
The prognostic significance of chromosomal translocations, particularly t(1;19) (q23;p13), was evaluated in children with pre-B… (More)
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Highly Cited
1990
Highly Cited
1990
In earlier studies of the cytogenetic characteristics of leukemic lymphoblasts from children with pre-B-cell acute lymphoblastic… (More)
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Highly Cited
1984
Highly Cited
1984
Chromosome banding studies on 60 children with acute lymphocytic leukemia (ALL), including "null," pre-B, B, and T cell… (More)
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