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t(1;19)

A cytogenetic abnormality that involves a translocation between chromosomes 1 and 19.
National Institutes of Health

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2 relations
Chromosomes, Human, Pair 1Chromosomes, Human, Pair 19

Papers overview

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2012
2012
Immunophenotype and cytogenetic characteristics in the relationship between birth weight and childhood leukemia
High birth weight increases the risk of childhood acute lymphoid leukemia (ALL) through unknown mechanisms. Whether this risk is… 
2005
2005
Formation of der(19)t(1;19)(q23;p13) in acute lymphoblastic leukemia
The t(1;19)(q23;p13), which results in a fusion of TCF3 (previously E2A) at 19p13 with PBX1 at 1q23, is one of the most common… 
Highly Cited
2002
Highly Cited
2002
Gradient of E2A Activity in B-Cell Development
ABSTRACT The E2A locus is a frequent target of chromosomal translocations in B-cell acute lymphoblastic leukemia (B-ALL). E2A… 
1996
1996
Cytogenetic, cytomorphologic, and immunologic analysis in 55 children with acute lymphoblastic leukemia.
Highly Cited
1995
Highly Cited
1995
Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia.
We have investigated the alterations of p53 and ras genes including H-, K-, and N-ras genes in 22 acute lymphoblastic leukemia… 
1995
1995
Expression of the E2A-PBX1 fusion transcripts in t(1;19)(q23;p13) and der(19)t(1;19) at diagnosis and in remission of acute lymphoblastic leukemia with different B lineage immunophenotypes.
The chromosomal translocation t(1;19)(q23;p13) and its variant form der(19)t(1;19) found in 3-5% of acute lymphoblastic leukemia… 
Highly Cited
1994
Highly Cited
1994
Leukemia-associated changes identified by quantitative flow cytometry: I. CD10 expression.
We have compared CD10 antigen expression in normal fetal bone marrow with that of B-linage acute lymphoblastic leukemia (ALL… 
1993
1993
Age- and gender-related heterogeneity of cancer chromosome aberrations.
Highly Cited
1989
Highly Cited
1989
Definition of subchromosomal intervals around the myotonic dystrophy gene region at 19q.
1986
1986
A t(1;19) chromosome translocation in three cases of human malignant melanoma.
Abnormalities of chromosome 1, including trisomy for all or a portion of the long arm, have been frequently reported in many… 
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