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surfactant homeostasis

Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli. [PMID:9751757]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Comparative pulmonary response to inhaled nanostructures: considerations on test design and endpoints
Recently there has been increased concern and focus on the toxicity of engineered nanoparticulates (NPs). The tendency of NPs to… 
Highly Cited
2005
Highly Cited
2005
Surfactant protein D influences surfactant ultrastructure and uptake by alveolar type II cells.
Surfactant protein D (SP-D) is a member of the collectin family of the innate host defense proteins. In the lung, SP-D is… 
Highly Cited
2004
Highly Cited
2004
Stat-3 is required for pulmonary homeostasis during hyperoxia.
Acute lung injury syndromes remain common causes of morbidity and mortality in adults and children. Cellular and physiologic… 
Highly Cited
2002
Highly Cited
2002
Tissue Distribution of Surfactant Proteins A and D in the Mouse
Surfactant proteins A and D, collagen-like lectins (collectins), were first isolated from the lung. In the lung, SP-A and SP-D… 
Highly Cited
2001
Highly Cited
2001
SP-D and GM-CSF regulate surfactant homeostasis via distinct mechanisms.
Both surfactant protein (SP) D and granulocyte-macrophage colony-stimulating factor (GM-CSF) influence pulmonary surfactant… 
Highly Cited
2000
Highly Cited
2000
Distinct changes in pulmonary surfactant homeostasis in common beta-chain- and GM-CSF-deficient mice.
Pulmonary alveolar proteinosis (PAP) is caused by inactivation of either granulocyte-macrophage colony-stimulating factor (GM-CSF… 
Highly Cited
1998
Highly Cited
1998
Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D.
Surfactant protein D (SP-D) is one of two collectins found in the pulmonary alveolus. On the basis of homology with other… 
Review
1998
Review
1998
Regulation of surfactant protein gene transcription.
Highly Cited
1997
Highly Cited
1997
Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung.
Interleukin-4 (IL-4) is a pleotrophic cytokine which is increased during lung injury and inflammation. Epithelial cell morphology… 
Review
1995
Review
1995
Human surfactant protein B: structure, function, regulation, and genetic disease.
Elucidation of the structure and function of the hydrophobic surfactant protein (SP-B) and the SP-B gene has provided critical… 
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