superoxide-generating NADPH oxidase

Reactive oxygen species (ROS) are at the centre of many physiological and pathological processes. NOX1, a ROS-producing NADPH… (More)

Reactive oxygen species (ROS) play a major role in drug-, noise-, and age-dependent hearing loss, but the source of ROS in the… (More)

Nox1 and Nox4, homologues of the leukocyte NADPH oxidase subunit Nox2 (gp91phox) mediate superoxide anion formation in various… (More)

The activated Ras oncogene can transform various mammalian cells and has been implicated in development of a high population of… (More)

Superoxide and its derivatives are increasingly implicated in the regulation of physiological functions from oxygen sensing and… (More)

Reactive oxygen species (ROS) generated in some non-phagocytic cells are implicated in mitogenic signalling and cancer. Many… (More)

The phagocyte NADPH oxidase flavocytochrome b558 is a membrane-bound heterodimer comprised of a glycosylated subunit, gp91(phox… (More)

Low-level generation of reactive oxygen species (ROS) by endothelial cells in response to a variety of stimuli has been observed… (More)

Human fibroblasts have the capacity to release superoxide radicals upon stimulation of an electron transport system similar to… (More)

The membrane potential of cytoplasts, derived from human neutrophils, was depolarized by the activation of the superoxide… (More)