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[Chemical reaction: See text] The synthesis of stevastelin B3 (2) and B (5) are described. In a first approach, epoxy… Expand Abstract A synthetic approach to the -membered stevastelins, a novel class of immunosuppressant agents, is reported based on… Expand The total synthesis and an unambiguous structure confirmation of stevastelin B 1, a novel 15-membered cyclic depsipeptide, are… Expand A synthesis of the stevastelins, a novel class of immunosuppressant agents, is reported based on a macrolactonization approach… Expand BACKGROUND
Since the molecular target of the immunosuppressive reagents FK506 and cyclosporin A was revealed to be protein… Expand Stevastelin B, obtained from a culture of a Penicillium sp. NK374186, is a novel depsipeptide containing three amino acids and 3… Expand