Skip to search formSkip to main contentSkip to account menu

statine

Known as: 4-amino-3-hydroxy-6-methylheptanoic acid 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Amino Acids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
A simple microscale method for determining the relative stereochemistry of statine units.
A simple method to determine the relative stereochemistry of statine amino acids (gamma-amino-beta-hydroxyacids) by using (1)H… 
Highly Cited
1993
Highly Cited
1993
Inhibitors of the isoprenylated protein endoprotease.
The isoprenylation pathway requires an endoprotease that cleaves the modified protein at the isoprenylated cysteine residue. This… 
1990
1990
The selectivity of statine-based inhibitors against various human aspartic proteinases.
The interactions of five human enzymes (renin, pepsin, gastricsin, cathepsin D and cathepsin E) and the aspartic proteinase from… 
1988
1988
Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases.
Two new inhibitors, 4 and 5, of the aspartic proteinase porcine pepsin were synthesized. These compounds, which span the P4-P'3… 
1987
1987
Novel renin inhibitors containing analogues of statine retro-inverted at the C-termini: specificity at the P2 histidine site.
Substituted 1,3- and 1,4-diamines were prepared from epoxides derived from Boc-leucine or Boc-cyclohexylalanine. These diamines… 
1986
1986
Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.
Five new cathepsin D inhibitors were synthesized and tested as inhibitors of bovine cathepsin D. The compounds were derived by… 
Highly Cited
1985
Highly Cited
1985
Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.
Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino… 
Highly Cited
1984
Highly Cited
1984
Statine-containing renin inhibitor. Dissociation of blood pressure lowering and renin inhibition in sodium-deficient dogs.
Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2 is a new, potent, specific statine -containing renin inhibitor. In vitro, the ID50 needed to… 
1979
1979
Synthesis of all the stereoisomers of statine (4-amino-3-hydroxy-6-methylheptanoic acid). Inhibition of pepsin activity by N-carbobenzoxy-L-valyl-L-valyl-statine derived from the four stereoisomers.
Synthesis of all four stereoisomers of the novel amino acid statine, 4-amino-3-hydroxy-6-methylheptanoic acid, found in pepstatin… 
1973
1973
Letter: X-ray structure determination of 4-amino-3-hydroxy-6-methylheptanoic acid, an amine component of pepstatin.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)