statine

Known as: 4-amino-3-hydroxy-6-methylheptanoic acid 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2016
051019732016

Papers overview

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2004
2004
Statine-based inhibitors of Plasmepsin II (PLMII) coupled with Primaquine have been designed using the 'double-drug' approach… (More)
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2003
2003
We describe the development of statine-based peptidomimetic inhibitors of human beta-secretase (BACE). The conversion of the… (More)
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2003
2003
Utilizing structure-based techniques and solid-phase synthesis, statine-based tetrapeptide BACE inhibitors were designed and… (More)
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1998
1998
An encoded 13,020-member combinatorial library was synthesized containing a statine core. Evaluation of this library with… (More)
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1995
1995
The discovery that the protease from the human immunodeficiency virus (HIV) belongs to the aspartic protease family has generated… (More)
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1990
1990
The interactions of five human enzymes (renin, pepsin, gastricsin, cathepsin D and cathepsin E) and the aspartic proteinase from… (More)
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1989
1989
The conformation of a statine-containing renin inhibitor complexed with the aspartic proteinase from the fungus Endothia… (More)
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1986
1986
Dipeptide and tripeptide derivatives containing a statine residue were synthesized as inhibitors of human renin. ES-305, bis[(1… (More)
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1984
1984
Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2 is a new, potent, specific statine -containing renin inhibitor. In vitro, the ID50 needed to… (More)
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1983
1983
The proteolytic enzyme renin (EC3.4.99.19) cleaves the protein substrate angiotensinogen to yield angiotensin I, the decapeptide… (More)
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