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statine

Known as: 4-amino-3-hydroxy-6-methylheptanoic acid 
 
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
Cyclic peptide natural products contain a variety of conserved, nonproteinogenic structural elements such as d-amino acids and… Expand
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2009
2009
An asymmetric synthesis of anti-aldol segments via a nonaldol route is described. The strategy involves a highly… Expand
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2008
2008
A simple method to determine the relative stereochemistry of statine amino acids (gamma-amino-beta-hydroxyacids) by using (1)H… Expand
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2004
2004
Statine-based inhibitors of Plasmepsin II (PLMII) coupled with Primaquine have been designed using the 'double-drug' approach… Expand
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2004
2004
Picomolar to low nanomolar inhibitors of the two aspartic proteases plasmepsin (Plm) I and II, from the malaria parasite… Expand
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1998
1998
An encoded 13,020-member combinatorial library was synthesized containing a statine core. Evaluation of this library with… Expand
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Highly Cited
1995
Highly Cited
1995
The discovery that the protease from the human immunodeficiency virus (HIV) belongs to the aspartic protease family has generated… Expand
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1985
1985
Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino… Expand
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1984
1984
Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2 is a new, potent, specific statine -containing renin inhibitor. In vitro, the ID50 needed to… Expand
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1983
1983
The proteolytic enzyme renin (EC3.4.99.19) cleaves the protein substrate angiotensinogen to yield angiotensin I, the decapeptide… Expand
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