squalene synthase activity

Known as: squalene synthetase activity 
Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate. [EC:2.5.1.21]
National Institutes of Health

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Topic mentions per year

1979-2013
012319792013

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2013
2013
Withania somnifera commonly known as Ashwagandha, is held in high repute in traditional Indian medicine, largely due to the… (More)
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2006
2006
We investigated the effects of EP2306 and EP2302, two novel 2-biphenylmorpholine derivatives, on squalene synthase activity in… (More)
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1997
1997
Recent studies have shown that endotoxin (LPS) administration to Syrian hamsters markedly increased hepatic HMG-CoA reductase… (More)
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1997
1997
Biosynthesis of polyprenols was followed in the erg mutants of Saccharomyces cerevisiae impaired in various steps of the… (More)
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1995
1995
Squalene synthetase (SQS, EC 2.5.1.21) catalyzes the first committed step in the formation of cholesterol and thus represents an… (More)
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1992
1992
The principle of selective elution from a solid phase has been exploited to develop an assay for the determination of squalene… (More)
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1991
1991
The ERG9 gene of Saccharomyces cerevisiae has been cloned by complementation of the erg9-1 mutation which affects squalene… (More)
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1988
1988
Addition of elicitor, cell wall fragments of the fungus Phytophthora parasitica, to tobacco cell suspension cultures (Nicotiana… (More)
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1986
1986
Squalene synthetase activity in liver microsomes from rats sacrificed at three different times of the diurnal cycle showed no… (More)
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1979
1979
Squalene synthetase (farnesyltransferase; farnesyl diphosphate:farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21), the enzyme… (More)
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