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squalamine lactate

The lactate salt form of squalamine, an aminosterol isolated from tissues of the dogfish shark Squalus acanthias. Possessing anti-angiogenic… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Angiogenesis InhibitorsCholestanolsLactatessqualamine

Narrower (1)

MSI-1256F

Papers overview

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2015
2015
Final Results from a Phase 2 Study of Squalamine Lactate Ophthalmic Solution 0.2% (OHR-102) in the Treatment of Neovascular Age-related Macular Degeneration (AMD)
2007
2007
Squalamine lactate for the treatment of age-related macular degeneration
Squalamine lactate (Evizon™, Genaera, PA, USA) is a systemically administered antiangiogenic compound that is among the group of… 
Review
2006
Review
2006
Squalamine lactate for exudative age-related macular degeneration.
2005
2005
Apparent receptor-mediated activation of Ca2+-dependent conductive Cl- transport by shark-derived polyaminosterols.
The shark liver antimicrobial polyaminosterol squalamine is an angiogenesis inhibitor under clinical investigation as an anti… 
2005
2005
A Phase II, Multi–Center, Randomized, Controlled, Masked Study of the Effects of Squalamine Lactate in Combination With Visudyne® in Patients With Subfoveal Choroidal Neovascularization Associated…
2005
2005
A Phase 2 Multi–Dose Pharmacokinetic Study of MSI–1256F (Squalamine Lactate) for the Treatment of Subfoveal Choroidal Neovascularization Associated With Age–Related Macular Degeneration (AMD)
2005
2005
Squalamine lactate preserves vision in phase II trial
Key Biscayne, FL—In a small, phase II clinical trial of squalamine lactate (Evizon, Genaera Corp.), a systemically delivered drug… 
2004
2004
A Phase I/II Trial of Intravenous Squalamine Lactate for Treatment of Choroidal Neovascularization in Age Related Macular Degeneration (ARMD).
2003
2003
Determination of degradation products of squalamine lactate using LC/MS.
2002
2002
The synthesis of spermine analogs of the shark aminosterol squalamine
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