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sprouting angiogenesis

The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0204019972017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.
Angiopoietin-2 (ANG-2) is a key regulator of angiogenesis that exerts context-dependent effects on ECs. ANG-2 binds the… (More)
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2012
2012
S1P1 inhibits sprouting angiogenesis during vascular development.
Coordination between the vascular system and forming organs is essential for proper embryonic development. The vasculature… (More)
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Highly Cited
2011
Highly Cited
2011
Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein
Angiogenesis, the formation of new blood vessels from pre-existing vessels, is critical to most physiological processes and many… (More)
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Highly Cited
2010
Highly Cited
2010
Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.
Inhibition of angiopoietin-2 (Ang2) can slow tumor growth, but the underlying mechanism is not fully understood. Because Ang2 is… (More)
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Highly Cited
2008
Highly Cited
2008
VEGF and endothelial guidance in angiogenic sprouting.
The cellular actions of VEGF need to be coordinated to guide vascular patterning during sprouting angiogenesis. Individual… (More)
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Highly Cited
2007
Highly Cited
2007
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
In sprouting angiogenesis, specialized endothelial tip cells lead the outgrowth of blood-vessel sprouts towards gradients of… (More)
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Highly Cited
2007
Highly Cited
2007
Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis.
Netrins are secreted molecules with roles in axonal growth and angiogenesis. The Netrin receptor UNC5B is required during… (More)
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2001
2001
Embryonic Stem Cell-Derived Embryoid Bodies Development in Collagen Gels Recapitulates Sprouting Angiogenesis
The formation of new blood vessels proceeds by both vasculogenesis and angiogenesis. The development of models, which fully… (More)
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Highly Cited
1999
Highly Cited
1999
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis.
Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon guidance and bundling in the… (More)
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Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 induces sprouting angiogenesis in vitro
Sprouting of new capillaries from pre-existing blood vessels is a hallmark of angiogenesis during embryonic development and solid… (More)
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