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sphingosine 1-phosphate

Known as: (2-Amino-3-Hydroxy-Octadec-4-Enoxy)Phosphonic Acid, (2S,3R,4E)-2-Amino-3-Hydroxyoctadec-4-En-1-Yl Dihydrogen Phosphate, Sphing-4-Enine 1-Phosphate 
A bioactive sphingolipid comprised of a sphingosine with a phosphate group attached to the carbon at position 1. Sphingosine 1-phosphate (S1P) binds… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Severe influenza remains unusual in its virulence for humans. Complications or ultimately death arising from these infections are… Expand
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Highly Cited
2007
Highly Cited
2007
Lymphocytes require sphingosine-1-phosphate (S1P) receptor-1 to exit lymphoid organs, but the source(s) of extracellular S1P and… Expand
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Review
2003
Review
2003
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals… Expand
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Highly Cited
2002
Highly Cited
2002
Blood lymphocyte numbers, essential for the development of efficient immune responses, are maintained by recirculation through… Expand
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Highly Cited
2002
Highly Cited
2002
Immunosuppressant drugs such as cyclosporin have allowed widespread organ transplantation, but their utility remains limited by… Expand
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Review
2000
Review
2000
The universality of calcium as an intracellular messenger depends on its enormous versatility. Cells have a calcium signalling… Expand
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Highly Cited
2000
Highly Cited
2000
Sphingolipid signaling pathways have been implicated in many critical cellular events. Sphingosine-1-phosphate (SPP), a… Expand
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Highly Cited
1999
Highly Cited
1999
Vascular endothelial cells undergo morphogenesis into capillary networks in response to angiogenic factors. We show here that… Expand
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Highly Cited
1998
Highly Cited
1998
The sphingolipid metabolite sphingosine-1-phosphate (SPP) has been implicated as a second messenger in cell proliferation and… Expand
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Highly Cited
1996
Highly Cited
1996
CERAMIDE is an important regulatory participant of programmed cell death (apoptosis) induced by tumour-necrosis factor (TNF… Expand
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