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sphingosine 1-phosphate

Known as: (2-Amino-3-Hydroxy-Octadec-4-Enoxy)Phosphonic Acid, (2S,3R,4E)-2-Amino-3-Hydroxyoctadec-4-En-1-Yl Dihydrogen Phosphate, Sphing-4-Enine 1-Phosphate 
A bioactive sphingolipid comprised of a sphingosine with a phosphate group attached to the carbon at position 1. Sphingosine 1-phosphate (S1P) binds… 
National Institutes of Health

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3 relations

Broader (2)

LysophospholipidsSphingosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Involvement of Sphingolipids in Ethanol Neurotoxicity in the Developing Brain
Ethanol-induced neuronal death during a sensitive period of brain development is considered one of the significant causes of… 
2013
2013
Role of Sphingosine 1-Phosphate (S1P) Receptor 1 in Experimental Autoimmune Encephalomyelitis —I
Therapeutic administration of fingolimod hydrochloride (FTY720), the functional antagonist at sphingosine 1-phosphate (S1P… 
2012
2012
Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR 4 antagonists in mice
CXCL12 and VCAM1 retain hematopoietic stem cells (HSCs) in the BM, but the factors mediating HSC egress from the BM to the blood… 
Review
2008
Review
2008
The enigma of sphingosine 1-phosphate synthesis: a novel role for endothelial sphingosine kinases.
See related article, pages 669–676 Sphingosine 1-phosphate (S1P) is well known as a key sphingolipid messenger molecule in the… 
2006
2006
Rac 1 Modulates Sphingosine 1-Phosphate-mediated Activation of Phosphoinositide 3-Kinase / Akt Signaling Pathways in Vascular Endothelial Cells *
Sphingosine 1-phosphate (S1P) is a platelet-derived sphingolipid that activatesG protein-coupled S1P receptors and initiates a… 
2002
2002
Sphingosine-1-Phosphate, a Platelet-Derived Lysophospholipid Mediator, Negatively Regulates Cellular Rac Activity and Cell Migration in Vascular Smooth Muscle Cells
Previous studies demonstrated that sphingosine-1-phosphate (S1P) induced migration of human umbilical vein endothelial cells… 
2002
2002
The Role of TNF α and Sphingolipid Signaling in Cardiac Hypoxia : Evidence that Cardiomyocytes Release TNF α and Sphingosine
Sphingosine (SPH) is a naturally occurring signaling molecule thought to be responsible for the negative inotropic and… 
2000
2000
Effects of sphingosine 1-phosphate, a naturally occurring biologically active lysophospholipid, on the rat cardiovascular system.
Recent studies have indicated that sphingosine 1-phosphate (Sph-1-P) is released into the blood flow from activated platelets… 
1970
1970
Metabolism of sphingosine bases. XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine 1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate.
1965
1965
THE COMPONENT FATTY ACIDS OF LIPIDS FROM SOME STREPTOMYCES SPP.