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Sphingosine

Known as: Sphingosine [Chemical/Ingredient], 4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-, 4 Sphingenine 
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in… Expand
National Institutes of Health

Papers overview

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2017
2017
Summary Chronic pulmonary colonization with bacterial pathogens, particularly Pseudomonas aeruginosa, is the primary cause of… Expand
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Highly Cited
2012
Highly Cited
2012
Abstract Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that regulates inflammatory responses to injury and infection. IL… Expand
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Highly Cited
2011
Highly Cited
2011
Functionalisation of the surface of orthopaedic implants with nanotopographies that could stimulate in situ osteogenic… Expand
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Highly Cited
2009
Highly Cited
2009
Consensus exists that lipids must play key functions in synaptic activity but precise mechanistic information is limited. Acid… Expand
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Highly Cited
2001
Highly Cited
2001
We propose a new mechanism for sphingosine-induced apoptosis, involving relocation of lysosomal hydrolases to the cytosol. Owing… Expand
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Highly Cited
1996
Highly Cited
1996
In the study of apoptosis initiated by various signals including ligands binding to cell membrane receptors such as Fas and TNFRI… Expand
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Review
1995
Review
1995
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been… Expand
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Highly Cited
1994
Highly Cited
1994
The interactions of ceramides with phosphatidate and lysophosphatidate in the regulation of signal transduction in rat… Expand
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Review
1989
Review
1989
Sphingosine, the backbone moiety of sphingomyelin, gangliosides and other complex sphingolipids, is a potent inhibitor of protein… Expand
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Highly Cited
1978
Highly Cited
1978
Total glycosphingolipids (glucosylceramides) were isolated from both pig (ear) and human (leg) epidermis and each separated into… Expand
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