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Sphingosine

Known as: Sphingosine [Chemical/Ingredient], 4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-, 4 Sphingenine 
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Summary Chronic pulmonary colonization with bacterial pathogens, particularly Pseudomonas aeruginosa, is the primary cause of… Expand
Highly Cited
2011
Highly Cited
2011
Functionalisation of the surface of orthopaedic implants with nanotopographies that could stimulate in situ osteogenic… Expand
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Review
2008
Review
2008
“Sphingosin” was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1… Expand
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Highly Cited
2001
Highly Cited
2001
We propose a new mechanism for sphingosine-induced apoptosis, involving relocation of lysosomal hydrolases to the cytosol. Owing… Expand
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Highly Cited
1996
Highly Cited
1996
In the study of apoptosis initiated by various signals including ligands binding to cell membrane receptors such as Fas and TNFRI… Expand
Review
1995
Review
1995
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been… Expand
Highly Cited
1991
Highly Cited
1991
Recent studies suggest the existence of a signal transduction pathway involving sphingomyelin and derivatives (Kolesnick, R. N… Expand
Review
1989
Review
1989
Sphingosine, the backbone moiety of sphingomyelin, gangliosides and other complex sphingolipids, is a potent inhibitor of protein… Expand
Highly Cited
1988
Highly Cited
1988
Amphipathic compounds containing N‐acetylneuraminic acid (sialic acid) [for example, D‐N‐acetylneuraminyl‐(α2‐1)‐2S, 3R,4E‐2‐N… Expand
Highly Cited
1978
Highly Cited
1978
Total glycosphingolipids (glucosylceramides) were isolated from both pig (ear) and human (leg) epidermis and each separated into… Expand