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Sphingosine

Known as: Sphingosine [Chemical/Ingredient], 4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-, 4 Sphingenine 
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (39)

1-deoxysphinganine1-deoxysphingosine2,3-N-octanoylsphingosine2-amino-3,5-dihydroxyoctadecane

Broader (1)

Amino Alcohols
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes.
Highly Cited
2010
Highly Cited
2010
Individual fumonisin exposure and sphingoid base levels in rural populations consuming maize in South Africa.
Highly Cited
2002
Highly Cited
2002
Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides).
Highly Cited
2001
Highly Cited
2001
Sphingosine-induced apoptosis is dependent on lysosomal proteases.
We propose a new mechanism for sphingosine-induced apoptosis, involving relocation of lysosomal hydrolases to the cytosol. Owing… 
Highly Cited
1998
Highly Cited
1998
Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds.
Highly Cited
1996
Highly Cited
1996
Sphingosine and its methylated derivative N,N‐dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines
In the study of apoptosis initiated by various signals including ligands binding to cell membrane receptors such as Fas and TNFRI… 
Review
1995
Review
1995
Functional role of glycosphingolipids in cell recognition and signaling.
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been… 
Highly Cited
1994
Highly Cited
1994
Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts.
Highly Cited
1988
Highly Cited
1988
Synthetic Sialyl Compounds as Well as Natural Gangliosides Induce Neuritogenesis in a Mouse Neuroblastoma Cell Line (Neuro2a)
Amphipathic compounds containing N‐acetylneuraminic acid (sialic acid) [for example, D‐N‐acetylneuraminyl‐(α2‐1)‐2S, 3R,4E‐2‐N… 
Highly Cited
1978
Highly Cited
1978
Glycosphingolipids and ceramides in human and pig epidermis.
Total glycosphingolipids (glucosylceramides) were isolated from both pig (ear) and human (leg) epidermis and each separated into… 
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