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Sphingosine

Known as: Sphingosine [Chemical/Ingredient], 4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-, 4 Sphingenine 
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (39)

1-deoxysphinganine1-deoxysphingosine2,3-N-octanoylsphingosine2-amino-3,5-dihydroxyoctadecane

Broader (1)

Amino Alcohols
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The role of sphingolipids and lipid rafts in determining cell fate
2006
2006
Development of a new method for the analysis of sphinganine and sphingosine in urine and tissues.
The fumonisins are inhibitors of de novo sphingolipid biosynthesis in vitro and in vivo and thus possibly interfere with the… 
Review
1998
Review
1998
The use of FT-IR for quantitative studies of the apparent pKa of lipid carboxyl groups and the dehydration degree of the phosphate group of phospholipids.
Highly Cited
1998
Highly Cited
1998
Sphingosine Inhibits Voltage-operated Calcium Channels in GH4C1 Cells*
In the present study we investigated the mechanism of inhibitory action of sphingosine (SP) on voltage-activated calcium channels… 
1997
1997
Differential effects of sphingomyelinase and cell-permeable ceramide analogs on proliferation of Swiss 3T3 fibroblasts.
Review
1989
Review
1989
Modulation of protein kinase C and diverse cell functions by sphingosine--a pharmacologically interesting compound linking sphingolipids and signal transduction.
Highly Cited
1989
Highly Cited
1989
Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells.
Activators of protein kinase C (PKC) inhibit sodium transport in proximal tubules (PT) (M. Baum and S. R. Hays. Am. J. Physiol… 
1979
1979
ON THE COMPOSITION AND STRUCTURE OF INDIVIDUAL GANGLIOSIDES FROM THE BRAIN OF ELASMOBRANCHES
Gangliosides with a short carbohydrate chain: II3(NeuAc)2‐LacCer, II3(NeuAc)2‐GgOse3Cer, II3(NeuAc)3‐LacCer, II3NeuAc‐LacCer, and… 
1975
1975
3-Ketosphingolipids: application to the determination of sphingolipids which contain 4-sphingenine.
1972
1972
Synthesis of ceramides using N-hydroxysuccinimide esters.
Fatty acyl esters of N-hydroxysuccinimide have been used to directly N-acylate sphingenine or sphinganine, forming the… 
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