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2,3-N-octanoylsphingosine

Known as: 2,3-N-octanoyl-D-erythro-trans-sphingosine, C8-ceramide 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
LPS is a constituent of cell walls of Gram-negative bacteria that, acting through the CD14/TLR4 receptor complex, causes strong… Expand
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Highly Cited
2007
Highly Cited
2007
In the present study we used human breast cancer cell lines to assess the influence of ceramide and glucosylceramide (GC) on… Expand
Highly Cited
2004
Highly Cited
2004
Lipopolysaccharide (LPS) and interferon‐γ (IFN) treatment of C6 rat glioma cells increased the intracellular ceramide level and… Expand
Highly Cited
2001
Highly Cited
2001
Previous work in primary cell culture has shown that TNF-α and ceramide are involved in the signaling that induces tolerance to… Expand
Highly Cited
1997
Highly Cited
1997
Increased sensitivity to ionizing radiation has been shown to be due to defects in double-strand break repair and mutations in… Expand
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Highly Cited
1997
Highly Cited
1997
The generation of ceramides by the action of acidic and/or neutral sphingomyelinases has been implicated in many forms of… Expand
Highly Cited
1996
Highly Cited
1996
In the study of apoptosis initiated by various signals including ligands binding to cell membrane receptors such as Fas and TNFRI… Expand
Highly Cited
1996
Highly Cited
1996
Recent studies have demonstrated that ovarian follicle atresia occurs extensively before follicle selection into the avian… Expand
Highly Cited
1995
Highly Cited
1995
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are… Expand
Highly Cited
1993
Highly Cited
1993
Recent investigations suggest that tumor necrosis factor (TNF)-alpha may utilize the sphingomyelin pathway for signal… Expand