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sphingomyelin synthase activity

Known as: SMS2, phosphatidylcholine:ceramide cholinephosphotransferase activity, SM synthase activity 
Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin. [EC:2.7.8.27, RHEA:18768]
National Institutes of Health

Related topics

Related topics

1 relation
SGMS1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Role and Function of Sphingomyelin Biosynthesis in the Development of Cancer: CHAPTER THREE
2018
2018
2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity
2-Hydroxy-oleic acid (2OHOA) is a potent anticancer drug that induces cancer cell cycle arrest and apoptosis. Previous studies… 
2016
2016
Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum*
Sphingomyelin synthase (SMS) is the key enzyme for cross-talk between bioactive sphingolipids and glycerolipids. In mammals, SMS… 
2016
2016
Regulation of membrane KCNQ1/KCNE1 channel density by sphingomyelin synthase 1.
Sphingomyelin synthase (SMS) catalyzes the conversion of phosphatidylcholine and ceramide to sphingomyelin and diacylglycerol. We… 
2014
2014
Hybrid SWOT Approach for Strategic Planning and Formulation in China Worldwide Express Mail Service
2013
2013
Development of a quantitative biochemical and cellular sphingomyelin synthase assay using mass spectrometry.
Highly Cited
2011
Highly Cited
2011
Sphingomyelin Synthases Regulate Protein Trafficking and Secretion
Sphingomyelin synthases (SMS1 and 2) represent a class of enzymes that transfer a phosphocholine moiety from phosphatidylcholine… 
Highly Cited
2008
Highly Cited
2008
Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage.
2008
2008
Characterization of KlGRR1 and SMS1 Genes, Two New Elements of the Glucose Signaling Pathway of Kluyveromyces lactis
ABSTRACT The expression of the major glucose transporter gene, RAG1, is induced by glucose in Kluyveromyces lactis. This… 
Highly Cited
2007
Highly Cited
2007
Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.
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