sphingomyelin biosynthetic process

Known as: sphingomyelin synthesis, sphingomyelin formation, sphingomyelin anabolism 
The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. [ISBN:0198506732]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2016
02419772016

Papers overview

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2010
2010
Obesity increases the risk for hepatic steatosis. Recent studies have demonstrated that high fat diet (HFD) may affect… (More)
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2010
2010
Ceramide can be converted into sphingomyelin by sphingomyelin synthases (SMS) 1 and 2. In this study, we show that in human… (More)
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2008
2008
Oxysterol binding to liver X receptors (LXR) increases the transcription of genes involved in cholesterol efflux and disposal… (More)
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2006
2006
Plasma sphingomyelin (SM) has been suggested as a risk factor for coronary heart disease independent of cholesterol levels. A… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND In clinical studies, sphingomyelin (SM) plasma levels correlated with the occurrence of coronary heart disease… (More)
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2001
2001
We recently reported that the marked decrease in cellular ceramide in primary astrocytes is an early event associated with the… (More)
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2001
2001
Ceramide produced at the endoplasmic reticulum (ER) is transported to the lumen of the Golgi apparatus for conversion to… (More)
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2000
2000
We examined the effects of reduction of sphingomyelin level on cholesterol behavior in cells using 2 types of Chinese hamster… (More)
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1998
1998
Lysenin, a hemolytic protein derived from the earthworm Eisenia foetida, has a high affinity for sphingomyelin. Chinese hamster… (More)
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1995
1995
In several experimental and pathological conditions the cellular concentrations of cholesterol and sphingomyelin (SM) change… (More)
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