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- Publications
- Influence
Cholesterol interactions with phospholipids in membranes.
- H. Ohvo-Rekilä, B. Ramstedt, P. Leppimäki, J. Slotte
- Biology, Medicine
- Progress in lipid research
- 2002
Mammalian cell membranes are composed of a complex array of glycerophospholipids and sphingolipids that vary in head-group and acyl-chain composition. In a given cell type, membrane phospholipids may… Expand
Membrane properties of sphingomyelins
- B. Ramstedt, J. Slotte
- Chemistry, Medicine
- FEBS letters
- 30 October 2002
Sphingomyelin and phosphatidylcholine are important components in the external leaflet of cellular plasma membranes. In this review we compare the structure of these lipid molecules, with emphasis on… Expand
Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family.
- Satu H Helppolainen, K. Nurminen, +12 authors H. Nordlund
- Biology, Medicine
- The Biochemical journal
- 1 August 2007
Rhizobium etli CFN42 is a symbiotic nitrogen-fixing bacterium of the common bean Phaseolus vulgaris. The symbiotic plasmid p42d of R. etli comprises a gene encoding a putative (strept)avidin-like… Expand
Interaction of cholesterol with sphingomyelins and acyl-chain-matched phosphatidylcholines: a comparative study of the effect of the chain length.
- B. Ramstedt, J. Slotte
- Chemistry, Medicine
- Biophysical journal
- 1 February 1999
In this study we have synthesized sphingomyelins (SM) and phosphatidylcholines (PC) with amide-linked or sn-2 linked acyl chains with lengths from 14 to 24 carbons. The purpose was to examine how the… Expand
Biological functions of sphingomyelins.
- J. Slotte
- Biology, Medicine
- Progress in lipid research
- 1 October 2013
Sphingomyelin (SM) is a dominant sphingolipid in membranes of mammalian cells and this lipid class is specifically enriched in the plasma membrane, the endocytic recycling compartment, and the trans… Expand
Hepatocellular uptake of 3H-dihydromicrocystin-LR, a cyclic peptide toxin.
- J. Eriksson, L. Grönberg, S. Nygård, J. Slotte, J. Meriluoto
- Biology, Medicine
- Biochimica et biophysica acta
- 11 June 1990
The cellular uptake of microcystin-LR, a cyclic heptapeptide hepatotoxin from the cyanobacterium Microcystis aeruginosa, was studied by means of a radiolabelled derivative of the toxin.… Expand
Cyclodextrin-mediated removal of sterols from monolayers: effects of sterol structure and phospholipids on desorption rate.
In this study, we have examined a number of parameters which affect the rate of sterol desorption from a model membrane surface (a monolayer at the air/water interface) to cyclodextrins (CD) in the… Expand
Interaction of cholesterol with sphingomyelin in monolayers and vesicles.
- R. Bittman, C. R. Kasireddy, P. Mattjus, J. Slotte
- Chemistry, Medicine
- Biochemistry
- 4 October 1994
To understand the structural basis for the apparent strong interaction between cholesterol and sphingomyelin (SPM), we have synthesized an analogue of SPM, 3-deoxy-2-O-stearoyl-SPM, in which an… Expand
Membrane properties of D-erythro-N-acyl sphingomyelins and their corresponding dihydro species.
- M. Kuikka, B. Ramstedt, H. Ohvo-Rekilä, J. Tuuf, J. Slotte
- Chemistry, Medicine
- Biophysical journal
- 1 May 2001
We have prepared acyl chain-defined D-erythro-sphingomyelins and D-erythro-dihydrosphingomyelins and compared their properties in monolayer and bilayer membranes. Surface pressure/molecular area… Expand
A calorimetric study of binary mixtures of dihydrosphingomyelin and sterols, sphingomyelin, or phosphatidylcholine.
- T. Nyholm, Matts Nylund, J. Slotte
- Chemistry, Medicine
- Biophysical journal
- 1 May 2003
The thermotropic properties of binary mixtures of D-erythro-n-palmitoyl-dihydrosphingomyelin (16:0-DHSM), D-erythro-n-palmitoyl-sphingomyelin (16:0-SM), cholesterol, lathosterol, and… Expand