sphinganine

Known as: 2-Amino-1,3-Dihydroxyoctadecane, L-threo-dihydrosphingosine 
A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), L-threo-dihydrosphingosine competitively binds to the regulatory… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2018
010203019632018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates myriad important cellular processes, including growth, survival… (More)
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Highly Cited
2002
Highly Cited
2002
The longevity assurance gene (LAG1) and its homolog (LAC1) are required for acyl-CoA-dependent synthesis of ceramides containing… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine-1-phosphate (SPP) has diverse biological functions acting inside cells as a second messenger to regulate… (More)
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Highly Cited
1998
Highly Cited
1998
Sphingosine-1-phosphate (SPP) is a novel lipid messenger that has dual function. Intracellularly it regulates proliferation and… (More)
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Highly Cited
1996
Highly Cited
1996
The host-selective AAL toxins secreted by Alternaria alternata f sp lycopersici are primary chemical determinants in the… (More)
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Highly Cited
1993
Highly Cited
1993
Fumonisins, mycotoxins produced by Fusarium moniliforme and a number of other fungi, cause neuronal degeneration, liver and renal… (More)
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Highly Cited
1993
Highly Cited
1993
Ceramide activates a cytosolic protein phosphatase present in rat T9 glioma cells and rat brain. Ceramide-activated protein… (More)
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Highly Cited
1992
Highly Cited
1992
Serine palmitoyltransferase, 3-dehydrosphinganine reductase and sphinganine N-acyltransferase are responsible for the first steps… (More)
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1992
1992
Radioactively labeled N-[1-14C]-octanoyl-sphinganine and D-erythro-[3-3H]-sphinganine were administered in parallel experiments… (More)
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Highly Cited
1991
Highly Cited
1991
Culture materials and grains contaminated with certain isolates of Fusarium moniliforme cause equine leucoencephalomalacia… (More)
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