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sphinganine

Known as: 2-Amino-1,3-Dihydroxyoctadecane, L-Threo-Dihydrosphingosine 
A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), L-threo-dihydrosphingosine competitively binds to the regulatory… 
National Institutes of Health

Related topics

Related topics

3 relations
SPC 100270dihydrosphingosine

Broader (1)

safingol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
A practical synthesis of L-threo-dihydrosphingosine (safingol), an antineoplastic and antipsoriatic agent
LS-threo-Dihydrosphingosine, an antineoplastic and antipsoriatic drug, has been synthesized by the Henri reaction of hexadecanal… 
1985
1985
High performance liquid chromatographic analysis of long chain bases in intestinal glycolipids of adult and embryonic Japanese quails.
A new sensitive assay method for sphingoids, 4-D-hydroxysphinganine, sphingosine, and sphinganine, involving reversed phase HPLC… 
1983
1983
Analysis of sphingoid bases by reversed-phase high performance liquid chromatography.
A reversed-phase high performance liquid chromatography (HPLC) technique was developed for the analysis of sphingoid bases as… 
1974
1974
Studies on the desaturation of sphinganine. Ceramide and sphingomyelin metabolism in the rat and in BHK 21 cells in tissue culture.
1972
1972
Identification and quantitation of free ceramides in human platelets.
Free ceramides were isolated from human platelets. Their structures were unequivocally determined by gas-liquid chromatography… 
1970
1970
Gas-liquid chromatography-mass spectrometry of synthetic ceramides containing phytosphingosine.
Ceramides containing phytosphingosine as base and one of the fatty acids 16:0, 18:0, 20:0, 22:0, 23:0, and 24:0, were prepared by… 
1970
1970
Synthesis of D-dihydrosphingosine.
1970
1970
Gas--liquid chromatography--mass spectrometry of synthetic ceramides containing 2-hydroxy acids.
Ceramides containing either sphingosine or sphinganine and one of the 2-hydroxy acids, 14h:0, 16h:0, 18h:0, 20h:0, 22h:0, 24h:0… 
Highly Cited
1970
Highly Cited
1970
Metabolism of sphingosine bases. XIV. Sphinganine (dihydrosphingosine), an effective donor of the alk-1-enyl chain of plasmalogens.
1968
1968
The degradation of tritiated dihydrosphingosine in the intact rat.