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National Institutes of Health
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Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of…
Corpus ID: 2969142
The stress-activated protein kinase (SAPK) and mitogen-activated protein kinase (MAPK) cascades mediate cytotoxic and…
Pre-clamp cardioprotection by protein kinase C (PKC) inhibitor improves left ventricular function following canine normothermic arrest.
The Journal of cardiovascular surgery
Corpus ID: 21470050
Since protein kinase C (PKC) has been proven to be a mediator of neutrophil activation and of intracellular calcium homeostasis…
Stereo-specific analysis of a novel protein kinase C inhibitor.
T. A. Matches
Journal of pharmaceutical and biomedical analysis
Corpus ID: 10724972
SPC-100270 drug substance ((2S,3S)-2-aminooctadecane-1,3-diol) is a synthetic sphingosine analogue possessing limited ultraviolet…
SPC‐100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat
Transplant international : official journal of…
Corpus ID: 34155501
Abstract Recently, we reported that SPC‐100270, a sphingosine derivative and inhibitor of protein kinase C (50–90 μM) in mixed…
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