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specific granule

Known as: secondary granule 
Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid… 
National Institutes of Health

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specific granule membrane

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Highly Cited
2008
Highly Cited
2008
Reduced granulocyte activation with a heparin-coated device in an in vitro model of cardiopulmonary bypass.
Granulocyte activation during cardiopulmonary bypass (CPB), resulting in degranulation, may have adverse effects. Fresh whole… 
2001
2001
Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis
Abstract. A unique family of ribonucleases was identified by exhaustive screening of genomic and cDNA libraries using a probe… 
1996
1996
Neutrophil lactoferrin release induced by IgA immune complexes can be mediated either by Fc alpha receptors or by complement receptors through different pathways.
Our previous results showed that neutrophil secondary granule release, indicated by release of lactoferrin, was a slow process… 
1993
1993
Cloning and expression of the cDNA encoding mouse neutrophil gelatinase: demonstration of coordinate secondary granule protein gene expression during terminal neutrophil maturation.
The 92-kD form of human type IV collagenase (gelatinase) is a member of the matrix metalloproteinase family. It is restricted in… 
Highly Cited
1989
Highly Cited
1989
Interleukin-4 is a neutrophil activator.
1989
1989
Distribution of arachidonic acid in choline- and ethanolamine-containing phosphoglycerides in subfractionated human neutrophils.
Human neutrophils were fractionated on Percoll gradients and the various subcellular fractions were analyzed for phospholipid and… 
Highly Cited
1986
Highly Cited
1986
Preferential inhibition of primary granule release from bovine neutrophils by a Brucella abortus extract
A low-molecular-weight Brucella abortus extract (a nucleotidelike material) inhibited zymosan-elicited neutrophil degranulation… 
Highly Cited
1985
Highly Cited
1985
Cytochrome b translocation to human neutrophil plasma membranes and superoxide release. Differential effects of N-formylmethionylleucylphenylalanine, phorbol myristate acetate, and A23187.
Highly Cited
1983
Highly Cited
1983
Granulocyte activation by endotoxin. I. Correlation between adherence and other granulocyte functions, and role of endotoxin structure on biologic activity.
Reminiscent of high concentrations of formylated chemotactic peptides, another group of bacteria-derived products, the… 
1983
1983
The comparative responses of human polymorphonuclear leukocytes obtained by counterflow centrifugal elutriation and Ficoll-Hypaque density centrifugation. I. Resting volume, stimulus-induced…
: Standard isolation techniques for the human polymorphonuclear leukocyte (PMN) involve sequential exposure of cells to the… 
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