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sobuzoxane

Known as: 1,2-Bis(4-isobutoxycarbonyloxymethyl-3,5-dioxo-piperazin-1-yl)ethane, 1,2-bis(4-isobutoxycarbonyloxymethyl-3,5-dioxopiperazin-1-yl)ethane 
The orally available active prodrug of ICRF-154, a bisdioxopiperazine derivative, with cardioprotective and antineoplastic activities. Like other… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Antineoplastic AgentsPiperazinesTopoisomerase II Inhibitors

Narrower (1)

MST 16

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow… 
2014
2014
[Successful treatment with oral low-dose sobuzoxane and etoposide combined with rituximab in an elderly patient with HHV-8-negative primary effusion lymphoma-like lymphoma].
Primary effusion lymphoma (PEL) is a rare B-cell lymphoma, characterized by human herpes virus 8 (HHV8) infection and serous… 
Review
2012
Review
2012
Sobuzoxane-Containing Regimens Show Promising Response As Salvage Therapy for Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and Peripheral T-Cell Lymphoma, Not Otherwise Specified…
Abstract 4849 Background: Peripheral T-cell lymphoma (PTCL) is an intractable entity with limited response to CHOP-like regimens… 
2007
2007
[MTX-HOPE (methotrexate, hydrocortisone, vincristine, sobuzoxane, and etoposide) as a low-dose salvage chemotherapy for recurrent or refractory non-Hodgkin's lymphoma].
We conducted a clinical study of MTX-HOPE (day 1, methotrexate 20 mg per os (po); day 2, hydrocortisone 100 mg intravenous (iv… 
2006
2006
Crusted scabies in an adult T‐cell leukemia/lymphoma patient successfully treated with oral ivermectin
We report an adult T‐cell leukemia/lymphoma (ATL) patient whose crusted scabies was successfully treated with oral ivermectin… 
2001
2001
Long-Term Administration of Oral Low-Dose Topoisomerase II Inhibitors, MST-16 and VP-16, for Refractory or Relapsed Non-Hodgkin’s Lymphoma
It is known that the topoisomerase II inhibitors, MST-16 (sobuzoxane) and VP-16 (etoposide), are effective for the treatment of… 
1995
1995
Chapter 31. To Market, To Market – 1994
1992
1992
Phase II study: treatment of non-Hodgkin's lymphoma with an oral antitumor derivative of bis(2,6-dioxopiperazine).
BACKGROUND Although razoxane (ICRF-159), a derivative of bis(2,6-dioxopiperazine), has shown significant antitumor activity in… 
1991
1991
[Late phase II study of MST-16 (sobuzoxane) on malignant lymphoma].
Late phase II trial of MST-16 for malignant lymphoma was conducted by the multi-institutions collaboration. Out of 34 patients… 
1990
1990
[Phase I study of MST-16].
Phase I study with a new oral anticancer agents. MST-16 (Sobuzoxane), was conducted by 3 administration schedules: single, 5… 
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