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sobuzoxane

Known as: 1,2-Bis(4-isobutoxycarbonyloxymethyl-3,5-dioxo-piperazin-1-yl)ethane, 1,2-bis(4-isobutoxycarbonyloxymethyl-3,5-dioxopiperazin-1-yl)ethane 
The orally available active prodrug of ICRF-154, a bisdioxopiperazine derivative, with cardioprotective and antineoplastic activities. Like other… Expand
National Institutes of Health

Papers overview

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2016
2016
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow… Expand
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2014
2014
Primary effusion lymphoma (PEL) is a rare B-cell lymphoma, characterized by human herpes virus 8 (HHV8) infection and serous… Expand
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2013
2013
Anthracyclines (such as doxorubicin or daunorubicin) are among the most effective anticancer drugs, but their usefulness is… Expand
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2009
2009
Non-homologous end joining (NHEJ) and homologous recombination repair (HRR) are the main mechanisms involved in the processing of… Expand
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2007
2007
PurposeThe importance of understanding the mechanism of action of anticancer agents is sometimes overlooked in the pursuit of new… Expand
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2006
2006
Epidemiological evidence suggests that high consumption of Brassica genus vegetables, such as broccoli, cabbage, and Brussels… Expand
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Review
2004
Review
2004
Primary effusion lymphoma (PEL) is recognized as a unique clinicopathological entity associated with human herpesvirus 8 (HHV-8… Expand
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Review
1998
Review
1998
Catalytic inhibitors of mammalian DNA topoisomerase II have been found recently in natural and synthetic compounds. These… Expand
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Review
1998
Review
1998
Bis(2,6-dioxopiperazines) and other catalytic inhibitors of mammalian DNA topoisomerase II have recently been found in natural… Expand
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1992
1992
BACKGROUND Although razoxane (ICRF-159), a derivative of bis(2,6-dioxopiperazine), has shown significant antitumor activity in… Expand
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