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MST 16

Known as: MST-16 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Anthracyclines (such as doxorubicin or daunorubicin) are among the most effective anticancer drugs, but their usefulness is… Expand
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Review
2010
Review
2010
  • D. Lu, Tingren Lu
  • Anti-cancer agents in medicinal chemistry
  • 2010
  • Corpus ID: 25242315
Bisdioxopiperazine compounds, including ICRF-154 and razoxane (ICRF-159, Raz), are anticancer agents developed in the UK… Expand
2005
2005
BackgroundAnticancer bisdioxopiperazines, including ICRF-154, razoxane (Raz, ICRF-159) and ICRF-193, are a family of anticancer… Expand
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Review
2003
Review
2003
The nuclear enzyme DNA topoisomerase II is a major target for antineoplastic agents. All topoisomerase II-directed agents are… Expand
1999
1999
MST-16 [4,4-1,2-(ethanediyl)bis(1-isobutoxycarbonyl-oxy-methyl-2,6-pipera zinedione)], recently approved as an oral anticancer… Expand
Review
1998
Review
1998
Catalytic inhibitors of mammalian DNA topoisomerase II have been found recently in natural and synthetic compounds. These… Expand
Review
1998
Review
1998
  • T. Andoh
  • Biochimie
  • 1998
  • Corpus ID: 20968899
Bis(2,6-dioxopiperazines) and other catalytic inhibitors of mammalian DNA topoisomerase II have recently been found in natural… Expand
1993
1993
Background. MST‐16, a new orally administered bis(2,6‐dioxopiperazine) analogue and an inhibitor of topoisomerase II, was given… Expand
1992
1992
Adult T cell leukemia/lymphoma (ATLL) induced by human T cell leukemia virus I is resistant to conventional therapy. Six patients… Expand
Highly Cited
1991
Highly Cited
1991
Several recently developed derivatives of bis(2,6-dioxopiperazine) have been shown to be new antitumor agents and are currently… Expand
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